Natural killer cells in antiviral immunity
Natural killer (NK) cells play an important role in innate immune responses to viral infections.
Here, we review recent insights into the role of NK cells in viral infections, with particular …
Here, we review recent insights into the role of NK cells in viral infections, with particular …
Natural killer cell specificity for viral infections
Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …
HIV-1 and human genetic variation
Over the past four decades, research on the natural history of HIV infection has described
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …
Latency reversal plus natural killer cells diminish HIV reservoir in vivo
JT Kim, TH Zhang, C Carmona, B Lee, CS Seet… - Nature …, 2022 - nature.com
HIV is difficult to eradicate due to the persistence of a long-lived reservoir of latently infected
cells. Previous studies have shown that natural killer cells are important to inhibiting HIV …
cells. Previous studies have shown that natural killer cells are important to inhibiting HIV …
[HTML][HTML] Commensal bacteria stimulate antitumor responses via T cell cross-reactivity
Recent studies show gut microbiota modulate antitumor immune responses; one proposed
mechanism is cross-reactivity between antigens expressed in commensal bacteria and …
mechanism is cross-reactivity between antigens expressed in commensal bacteria and …
The role of innate immunity in the immunopathology and treatment of HBV infection
In this review we give a brief update on sensors recently determined to be capable of
detecting HBV, and examine how the virus represses the induction of pro-inflammatory …
detecting HBV, and examine how the virus represses the induction of pro-inflammatory …
[HTML][HTML] A public BCR present in a unique dual-receptor-expressing lymphocyte from type 1 diabetes patients encodes a potent T cell autoantigen
T and B cells are the two known lineages of adaptive immune cells. Here, we describe a
previously unknown lymphocyte that is a dual expresser (DE) of TCR and BCR and key …
previously unknown lymphocyte that is a dual expresser (DE) of TCR and BCR and key …
Innate receptors with high specificity for HLA class I–peptide complexes
Genetic studies associate killer cell immunoglobulin-like receptors (KIRs) and their HLA
class I ligands with a variety of human diseases. The basis for these associations and the …
class I ligands with a variety of human diseases. The basis for these associations and the …
NK cells in HIV disease
E Scully, G Alter - Current HIV/AIDS Reports, 2016 - Springer
Natural killer (NK) cells play a critical role in viral immunity. In the setting of HIV infection,
epidemiologic and functional evidence support a role for NK cells in both protection from …
epidemiologic and functional evidence support a role for NK cells in both protection from …
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44
Natural killer (NK) cells can recognize virus-infected and stressed cells using activating and
inhibitory receptors, many of which interact with HLA class I. Although early studies also …
inhibitory receptors, many of which interact with HLA class I. Although early studies also …