Microplastic pollution is becoming a major issue for human health due to the recent
discovery of microplastics in most ecosystems. Here, we review the sources, formation …

Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

Estrogens influence many physiological processes in mammals, including but not limited to
reproduction, cardiovascular health, bone integrity, cognition, and behavior. Given this …

The greater incidence of hypertension and coronary artery disease in men and
postmenopausal women compared with premenopausal women has been related, in part, to …

Microplastic contamination is a burgeoning environmental issue that poses serious threats
to animal and human health. Microplastics enter the human body through nasal, dermal, and …

Intestinal Ca2+ absorption is a crucial physiological process for maintaining bone
mineralization and Ca2+ homeostasis. It occurs through the transcellular and paracellular …

The characterization of estrogen receptor beta (ERβ) brought new insight into the
mechanisms underlying estrogen signaling. Estrogen induction of cell proliferation is a …

As early as the 1800s, the actions of estrogen have been implicated in the development and
progression of breast cancer. The estrogen receptor (ER) was identified in the late 1950s …

Recent studies indicate that the expression of ERβ in breast cancer is lower than in the
normal breast, suggesting that ERβ could play an important role in carcinogenesis. To …

The discovery of a second estrogen receptor (ER), designated ERβ (NR3A2), has redefined
our knowledge about the mechanisms underlying cellular signaling by estrogens and has …