Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the
complex processes influencing human biology. Proteins represent intermediate phenotypes …

Fluid protein biomarkers are important tools in clinical research and health care to support
diagnosis and to monitor patients. Especially within the field of dementia, novel biomarkers …

Human blood plasma provides a highly accessible window to the proteome of any individual
in health and disease. Since its inception in 2002, the Human Proteome Organization's …

Recent progress in both conceptual and technological approaches to human immunology
have rejuvenated a field that has long been in the shadow of the inbred mouse model. This …

G protein–coupled receptors (GPCRs) control critical cellular signaling pathways.
Therapeutic agents including anti-GPCR antibodies (Abs) are being developed to modulate …

The ability to detect and target β cells in vivo can substantially refine how diabetes is studied
and treated. However, the lack of specific probes still hampers a precise characterization of …

In this study, a high-performance anti-fouling coating based on poly adenine (polyA n) as
well as a highly specific cluster of differentiation 20 (CD20) epitope mimetic peptide (CN14) …

Body fluid biomarkers have great potential for different clinical purposes, including
diagnosis, prognosis, patient stratification and treatment effect monitoring. This is …

Autoimmune diseases are mostly characterized by autoantibodies in the patients' serum or
cerebrospinal fluid, representing diagnostic or prognostic biomarkers. For decades …

There is a clear clinical need for high-specificity plasma biomarkers for predicting risk of
venous thromboembolism (VTE), but thus far, such markers have remained elusive. Utilizing …