Wearable and implantable devices for cardiovascular healthcare: from monitoring to therapy based on flexible and stretchable electronics
Cardiovascular disease is the leading cause of death and has dramatically increased in
recent years. Continuous cardiac monitoring is particularly important for early diagnosis and …
recent years. Continuous cardiac monitoring is particularly important for early diagnosis and …
Injectable alginate hydrogels for cell delivery in tissue engineering
Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential
for use in biomedical applications. Their extracellular matrix-like features have been key …
for use in biomedical applications. Their extracellular matrix-like features have been key …
Epicardial FSTL1 reconstitution regenerates the adult mammalian heart
The elucidation of factors that activate the regeneration of the adult mammalian heart is of
major scientific and therapeutic importance. Here we found that epicardial cells contain a …
major scientific and therapeutic importance. Here we found that epicardial cells contain a …
Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review
The development of biomaterials for cardiac tissue engineering (CTE) is challenging,
primarily owing to the requirement of achieving a surface with favourable characteristics that …
primarily owing to the requirement of achieving a surface with favourable characteristics that …
Cardiac fibrosis: potential therapeutic targets
S Park, NB Nguyen, A Pezhouman, R Ardehali - Translational Research, 2019 - Elsevier
Cardiovascular disease is a leading cause of mortality in the world and is exacerbated by
the presence of cardiac fibrosis, defined by the accumulation of noncontractile extracellular …
the presence of cardiac fibrosis, defined by the accumulation of noncontractile extracellular …
Engineering the regenerative microenvironment with biomaterials
Modern synthetic biomaterials are being designed to integrate bioactive ligands within
hydrogel scaffolds for cells to respond and assimilate within the matrix. These advanced …
hydrogel scaffolds for cells to respond and assimilate within the matrix. These advanced …
Detachable microneedle patches deliver mesenchymal stromal cell factor-loaded nanoparticles for cardiac repair
Intramyocardial injection is a direct and efficient approach to deliver therapeutics to the
heart. However, the injected volume must be very limited, and there is injury to the injection …
heart. However, the injected volume must be very limited, and there is injury to the injection …
Electrically conductive carbon‐based (bio)‐nanomaterials for cardiac tissue engineering
A proper self‐regenerating capability is lacking in human cardiac tissue which along with the
alarming rate of deaths associated with cardiovascular disorders makes tissue engineering …
alarming rate of deaths associated with cardiovascular disorders makes tissue engineering …
Biomaterials in myocardial tissue engineering
Cardiovascular disease is the leading cause of death in the developed world, and as such
there is a pressing need for treatment options. Cardiac tissue engineering emerged from the …
there is a pressing need for treatment options. Cardiac tissue engineering emerged from the …
[HTML][HTML] Drug and cell delivery for cardiac regeneration
CL Hastings, ET Roche, E Ruiz-Hernandez… - Advanced drug delivery …, 2015 - Elsevier
The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …
congestive heart failure is a significant clinical issue in the modern era. This group of …