Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …
Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A Streptococcus
AF Johnson, CN LaRock - Frontiers in microbiology, 2021 - frontiersin.org
Group A Streptococcus (GAS; Streptococcus pyogenes) is a nearly ubiquitous human
pathogen responsible for a significant global disease burden. No vaccine exists, so …
pathogen responsible for a significant global disease burden. No vaccine exists, so …
The NLRP6 inflammasome recognizes lipoteichoic acid and regulates gram-positive pathogen infection
The activator and composition of the NLRP6 inflammasome remain poorly understood. We
find that lipoteichoic acid (LTA), a molecule produced by Gram-positive bacteria, binds and …
find that lipoteichoic acid (LTA), a molecule produced by Gram-positive bacteria, binds and …
Beta SARS-CoV-2 variant and BNT162b2 vaccine effectiveness in long-term care facilities in France
B Lefèvre, L Tondeur, Y Madec, R Grant… - The Lancet Healthy …, 2021 - thelancet.com
Variants of SARS-CoV-2 have emerged that are more transmissible than the original virus or
that exhibit some properties of immune escape, or both. The beta (B. 1.351) variant has …
that exhibit some properties of immune escape, or both. The beta (B. 1.351) variant has …
Streptococcus pyogenes Biofilm Growth In Vitro and In Vivo and Its Role in Colonization, Virulence, and Genetic Exchange
ABSTRACT Background. Group A streptococcus (GAS) commonly colonizes the oropharynx
and nonintact skin. However, colonization has been little studied and the role of biofilm …
and nonintact skin. However, colonization has been little studied and the role of biofilm …
[HTML][HTML] Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS)
G Orefici, F Cardona, CJ Cox, MW Cunningham - 2016 - europepmc.org
The inclusion of a chapter on pediatric autoimmune neuropsychiatric disorders associated
with streptococcal infections (or PANDAS) is essential to provide a history of the disease and …
with streptococcal infections (or PANDAS) is essential to provide a history of the disease and …
Antibiotics in necrotizing soft tissue infections
Necrotizing soft tissue infections (NSTIs) are rare life-threatening bacterial infections
characterized by an extensive necrosis of skin and subcutaneous tissues. Initial urgent …
characterized by an extensive necrosis of skin and subcutaneous tissues. Initial urgent …
Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells
Enterococcus faecalis is a frequent opportunistic pathogen of wounds, whose infections are
associated with biofilm formation, persistence, and recalcitrance toward treatment. We have …
associated with biofilm formation, persistence, and recalcitrance toward treatment. We have …
[HTML][HTML] Virulence-related transcriptional regulators of Streptococcus pyogenes
Control of virulence gene expression in S. pyogenes is under the charge of 13 two-
component regulatory systems and at least 30 transcriptional regulators known thus far …
component regulatory systems and at least 30 transcriptional regulators known thus far …
Gene fitness landscape of group A streptococcus during necrotizing myositis
Necrotizing fasciitis and myositis are devastating infections characterized by high mortality.
Group A streptococcus (GAS) is a common cause of these infections, but the molecular …
Group A streptococcus (GAS) is a common cause of these infections, but the molecular …