This review advances the discussion about the future of laboratory medicine in the 2020s. In
five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical …

The analysis of volatile organic compounds (VOCs) within breath for noninvasive disease
detection and monitoring is an emergent research field that has the potential to reshape …

There is overwhelming evidence that presence of cancer alters cellular metabolic
processes, and these changes are manifested in emitted volatile organic compound (VOC) …

Abstract Background The United Kingdom (UK) bowel cancer screening programme has
reduced mortality from colorectal cancer (CRC), but poor uptake with stool-based tests and …

Aim Faecal markers, such as the faecal immunochemical test for haemoglobin (FIT) and
faecal calprotectin (FCP), have been increasingly used to exclude colorectal cancer (CRC) …

Simple Summary Hepatobiliary cancers are notoriously difficult to detect, frequently leading
to diagnosis in later stages of disease when curative treatment is not an option. The currently …

Acute respiratory distress syndrome (ARDS) is the most severe form of acute lung injury,
responsible for high mortality and long-term morbidity. As a dynamic syndrome with multiple …

This article has an accompanying continuing medical education activity, also eligible for
MOC credit, on page e16. Learning Objective: Upon completion of this CME activity …

The electronic nose (eNose) is an instrument designed to mimic the human olfactory system.
Usage of eNose in medical applications is more popular than ever, due to its low costs and …

Current available methods for the clinical diagnosis of urinary tract infection (UTI) rely on a
urine dipstick test or culturing of pathogens. The dipstick test is rapid (available in 1–2 min) …