Computational Insights Into the Mechanism of EGCG's Binding and Inhibition of the TDP‐43 Aggregation
Misfolding and aggregation of TAR DNA‐binding protein, TDP‐43, is linked to devastating
proteinopathies such as ALS. Therefore, targeting TDP‐43's aggregation is significant for …
proteinopathies such as ALS. Therefore, targeting TDP‐43's aggregation is significant for …
Ensemble docking for intrinsically disordered proteins
A Dhar, TR Sisk, P Robustelli - bioRxiv, 2025 - biorxiv.org
Intrinsically disordered proteins (IDPs) are implicated in many human diseases and are
increasingly being pursued as drug targets. Conventional structure-based drug design …
increasingly being pursued as drug targets. Conventional structure-based drug design …