Epilepsy is a highly prevalent disease characterized by recurrent, spontaneous seizures.
Approximately one-third of epilepsy patients will not achieve seizure freedom with medical …

Presynaptic biogenic amine transporters mediate reuptake of released amines from the
synapse, thus regulating serotonin, dopamine and norepinephrine neurotransmission …

There is a high incidence of psychiatric comorbidity in people with epilepsy (PWE),
particularly depression. The manifold adverse consequences of comorbid depression have …

Attention-deficit/hyperactivity disorder (ADHD) in children with epilepsy is a common source
of impairment. Based on review of Medline indexed articles, meeting abstracts, and data …

Abstract A potassium N-(4-fluorobenzyl) N-(naphthalen-1-ylmethyl) dithiocarbamate ligand
(fbnm) has been isolated in a basic medium and its Ni (II), Cu (II), and Zn (II) complexes 1–3 …

People with epilepsy (PWE) are more likely to develop depression and both these complex
chronic diseases greatly affect health-related quality of life (QOL). This comorbidity …

Objective This paper is a systematic review on seizures under treatment with substances
licensed for major depression. Method Systematic review protocol is available in …

Background and Purpose Two of the most relevant unmet needs in epilepsy are represented
by the development of disease‐modifying drugs able to affect epileptogenesis and/or the …

Clinical evidence shows a strong, bidirectional comorbidity between depression and
epilepsy that is associated with decreased quality of life and responsivity to …

It is well established that the neurotransmitter norepinephrine (NE) has anticonvulsant
properties. However, NE may also have proconvulsant properties under some conditions …