Nephrons are the functional units which comprise the kidney. Each nephron contains a
number of physiologically unique populations of specialized epithelial cells that are …

Multiciliated cells (MCCS) form bundles of cilia and their activities are essential for the
proper development and physiology of many organ systems. Not surprisingly, defects in …

Retinoic acid (RA) is a metabolite of vitamin A (retinol) that plays various roles in
development to influence differentiation, patterning, and organogenesis. RA also serves as …

Kidney disease is a devastating condition affecting millions of people worldwide, where over
100,000 patients in the United States alone remain waiting for a lifesaving organ transplant …

Cilia are essential for the ontogeny and function of many tissues, including the kidney. Here,
we report that transcription factor ERRγ ortholog estrogen related receptor gamma a (Esrrγa) …

Ciliated cells serve vital functions in the body ranging from mechano-and chemo-sensing to
fluid propulsion. Specialized cells with bundles dozens to hundreds of motile cilia known as …

Retinoic acid is an active metabolite with significant physiological functions in human
development, immunity, vision, and skin health. In recent years, research on retinoic acid in …

Multiciliated cells (MCCs) serve many important functions, including fluid propulsion and
chemo-and mechanosensing. Diseases ranging from rare conditions to the recent COVID …

Cilia are hair-like organelles with vital physiological roles, and ciliogenesis defects underlie
a range of severe congenital malformations and human diseases. Here, we report that …

Zebrafish (Danio rerio) have emerged as an influential model for studying human epithelial
pathology, particularly because of their genetic similarity to humans and their unique …