Strategies for preparing albumin-based nanoparticles for multifunctional bioimaging and drug delivery

FF An, XH Zhang - Theranostics, 2017 - pmc.ncbi.nlm.nih.gov
Biosafety is the primary concern in clinical translation of nanomedicine. As an intrinsic
ingredient of human blood without immunogenicity and encouraged by its successful clinical …

Albumin nanostructures as advanced drug delivery systems

M Karimi, S Bahrami, SB Ravari… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: One of the biggest impacts that the nanotechnology has made on medicine and
biology, has been in the area of drug delivery systems (DDSs). Many drugs suffer from …

Photosensitizer‐conjugated albumin− polypyrrole nanoparticles for imaging‐guided in vivo photodynamic/photothermal therapy

X Song, C Liang, H Gong, Q Chen, C Wang, Z Liu - Small, 2015 - Wiley Online Library
Conjugated polymers with strong absorbance in the near‐infrared (NIR) region have been
widely explored as photothermal therapy agents due to their excellent photostability and …

Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration

B Son, M Kim, H Won, A Jung, J Kim, Y Koo… - Journal of …, 2023 - Springer
Background Basic fibroblast growth factor (bFGF) is one of the critical components
accelerating angiogenesis and tissue regeneration by promoting the migration of dermal …

Protein nanoparticles for therapeutic protein delivery

LPH Estrada, JA Champion - Biomaterials science, 2015 - pubs.rsc.org
Therapeutic proteins can face substantial challenges to their activity, requiring protein
modification or use of a delivery vehicle. Nanoparticles can significantly enhance delivery of …

Albumin nanoparticles as nanocarriers for drug delivery: Focusing on antibody and nanobody delivery and albumin-based drugs

E Karami, M Behdani, F Kazemi-Lomedasht - Journal of Drug Delivery …, 2020 - Elsevier
Given that albumin has important roles in human body, it can be used in the field of medicine
and disease treatment. In recent years, albumin is used as a carries in disease diagnosis …

Towards development of biobetter: L-asparaginase a case study

RK Tripathy, J Anakha, AH Pande - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
Background L-asparaginase (ASNase) has played a key role in the management of acute
lymphoblastic leukaemia (ALL). As an amidohydrolase, it catalyzes the hydrolysis of L …

Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders

M Placci, MI Giannotti, S Muro - Advanced drug delivery reviews, 2023 - Elsevier
Lysosomes play a central role in cellular homeostasis and alterations in this compartment
associate with many diseases. The most studied example is that of lysosomal storage …

Bone‐targeted delivery of cell‐penetrating‐RUNX2 fusion protein in osteoporosis model

S Kim, H Lee, J Hong, SHL Kim, E Kwon… - Advanced …, 2023 - Wiley Online Library
The onset of osteoporosis leads to a gradual decrease in bone density due to an imbalance
between bone formation and resorption. To achieve optimal drug efficacy with minimal side …

Doxorubicin-loaded, pH-sensitive albumin nanoparticles for lung cancer cell targeting

A Aziz, Y Sefidbakht, S Rezaei… - Journal of …, 2022 - Elsevier
In recent decades, scientific and medical communities have continuously sought new
methods and chemistries to improve the treatment of cancer. Among many types of …