Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice
M Ząbczyk, RAS Ariëns, A Undas - Cardiovascular research, 2023 - academic.oup.com
Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …
The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
[HTML][HTML] The suboptimal fibrinolytic response in COVID‐19 is dictated by high PAI‐1
CS Whyte, M Simpson, GB Morrow, CA Wallace… - Journal of Thrombosis …, 2022 - Elsevier
Background Severe COVID‐19 disease is associated with thrombotic complications and
extensive fibrin deposition. This study investigates whether the hemostatic complications in …
extensive fibrin deposition. This study investigates whether the hemostatic complications in …
Relative hypercoagulopathy of the SARS-CoV-2 beta and delta variants when compared to the less severe omicron variants is related to TEG parameters, the extent of …
LM Grobbelaar, A Kruger, C Venter… - … in thrombosis and …, 2022 - thieme-connect.com
Earlier variants of SARS-CoV-2 have been associated with hypercoagulability and an
extensive formation of fibrin amyloid microclots, which are considered to contribute to the …
extensive formation of fibrin amyloid microclots, which are considered to contribute to the …
Microvascular thrombosis as a critical factor in severe COVID-19
PP Wadowski, B Panzer, A Józkowicz… - International Journal of …, 2023 - mdpi.com
Platelet–endothelial interactions have a critical role in microcirculatory function, which
maintains tissue homeostasis. The subtle equilibrium between platelets and the vessel wall …
maintains tissue homeostasis. The subtle equilibrium between platelets and the vessel wall …
How does COVID-19 affect the heart?
Abstract Purpose of Review Cardiac consequences occur in both acute COVID-19 and post-
acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding about …
acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding about …
Molecular basis of clot retraction and its role in wound healing
AT Nurden - Thrombosis Research, 2023 - Elsevier
Clot retraction is important for the prevention of bleeding, in the manifestations of thrombosis
and for tissue repair. The molecular mechanisms behind clot formation are complex. Platelet …
and for tissue repair. The molecular mechanisms behind clot formation are complex. Platelet …
[HTML][HTML] Fibrinogen, fibrin, and fibrin degradation products in COVID-19
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the highly
pathogenic and highly transmissible human coronavirus that is the causative agent for the …
pathogenic and highly transmissible human coronavirus that is the causative agent for the …
[HTML][HTML] S1-Leitlinie long-/post-COVID
AR Koczulla, T Ankermann, U Behrends, P Berlit… - …, 2022 - thieme-connect.com
Die Deutsche Gesellschaft für Pneumologie hat 2021 die AWMF S1-Leitlinie Long-/Post-
COVID initiiert. In einem breiten interdisziplinären Ansatz wurde diese S1-Leitlinie …
COVID initiiert. In einem breiten interdisziplinären Ansatz wurde diese S1-Leitlinie …