Discovering molecular features of intrinsically disordered regions by using evolution for contrastive learning

AX Lu, AX Lu, I Pritišanac, T Zarin… - PLOS Computational …, 2022 - journals.plos.org
A major challenge to the characterization of intrinsically disordered regions (IDRs), which
are widespread in the proteome, but relatively poorly understood, is the identification of …

[PDF][PDF] FaSTPACE: a fast and scalable tool for peptide alignment and consensus extraction

HM Kotb, NE Davey - NAR Genomics and Bioinformatics, 2024 - academic.oup.com
Several novel high-throughput experimental techniques have been developed in recent
years that generate large datasets of putative biologically functional peptides. However …

Comparative in silico analysis of fungal and bacterial alkaline serine proteases: Insights into structure, function, and evolution

SE Mousavi, H Mohabatkar, M Behbahani - Iranian Journal of Science, 2024 - Springer
Serine proteases are an essential and immensely diverse group of enzymes found in many
different organisms, from mammals to viruses. Alkaline serine proteases (ASPs) are a type of …

Classification and Computational Analysis of Arabidopsis thaliana Sperm Cell-Specific F-Box Protein Gene 3p.AtFBP113

A Malik, A Gul, R Amir, F Munir, MM Babar… - Frontiers in …, 2020 - frontiersin.org
In plants, F-box proteins (FBPs) constitute one of the largest superfamilies of regulatory
proteins. Most F-box proteins are shown to be an integral part of SCF complexes, which …

Computational analysis of hypothetical proteins from Mycobacterium orygis identifies proteins with therapeutic and diagnostic potentials

A Mukherjee, P Dandapat, MZ Haque, S Mandal… - Animal Gene, 2023 - Elsevier
The genome of Mycobacterium orygis encodes 3767 proteins that includes 442 functionally
uncharacterized proteins, known as hypothetical proteins (HPs). These functionally …

Morbius: Platform-Adaptive Hardware Accelerator for Scalable Sequence Motif Discovery

SM Lim, E Aliaj, SW Jun - … Conference on e-Science (e-Science …, 2024 - ieeexplore.ieee.org
Motif finding is one of the fundamental tools of computational biology. Unfortunately, the
benefits of high-performance, low-power acceleration have not been available to this …

Using Motif-Based Features to Improve Signal Classification with Temporal Neural Networks

K Suresh, BK Iwana - Asian Conference on Pattern Recognition, 2023 - Springer
Time series motifs are repeated subsequences within a time series. Finding motifs is a large
field in time series recognition. For example, Matrix Profile is a robust and scalable data …

The evolution and exploration of intrinsically disordered and phase-separated protein states

CFW Chow, A Toth-Petroczy - The Three Functional States of Proteins, 2025 - Elsevier
Intrinsically disordered regions (IDRs) perform a vast repertoire of essential functions across
organisms in all kingdoms of life and, in many cases, function by driving the formation of …

[PDF][PDF] In silico structural and functional analysis of WRKY1 and WRKY3 genes in the selected cereal crops.

MT Pervez, ME Babar, J Iqbal, MJU Hasnain… - JAPS: Journal of …, 2021 - thejaps.org.pk
The WRKY family is one of the largest transcription factor families in higher plants and plays
an important role in the growth of plants, their development, and response to biotic and …

Recognizing significant Motifs of corona virus spike Proteins using computational approaches

M Nair, PR Anusree, A Babu - 2021 2nd Global Conference for …, 2021 - ieeexplore.ieee.org
The different mutated variants of Corona Virus (SARS-CoV-2), affected a large percentage of
the world population so far. On this light, any study on understanding the virus's immunity to …