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[HTML][HTML] Reactive oxygen species in osteoclast differentiation and possible pharmaceutical targets of ROS-mediated osteoclast diseases
Reactive oxygen species (ROS) and free radicals are essential for transmission of cell
signals and other physiological functions. However, excessive amounts of ROS can cause …
signals and other physiological functions. However, excessive amounts of ROS can cause …
Impact of Culture Medium on Cellular Interactions in in vitro Co-culture Systems
Co-culturing of cells in in vitro tissue models is widely used to study how they interact with
each other. These models serve to represent a variety of processes in the human body such …
each other. These models serve to represent a variety of processes in the human body such …
[HTML][HTML] Co–culture systems of osteoblasts and osteoclasts: Simulating in vitro bone remodeling in regenerative approaches
Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …
Recent developments of biomaterials for additive manufacturing of bone scaffolds
Recent years have witnessed surging demand for bone repair/regeneration implants due to
the increasing number of bone defects caused by trauma, cancer, infection, and arthritis …
the increasing number of bone defects caused by trauma, cancer, infection, and arthritis …
[HTML][HTML] Bone regeneration and oxidative stress: an updated overview
Bone tissue engineering is a complex domain that requires further investigation and benefits
from data obtained over past decades. The models are increasing in complexity as they …
from data obtained over past decades. The models are increasing in complexity as they …
Trabecular bone organoids: a micron-scale 'humanised'prototype designed to study the effects of microgravity and degeneration
Bone is a highly responsive organ, which continuously adapts to the environment it is
subjected to in order to withstand metabolic demands. These events are difficult to study in …
subjected to in order to withstand metabolic demands. These events are difficult to study in …
Designs and methodologies to recreate in vitro human gut microbiota models
The human gut microbiota is widely considered to be a metabolic organ hidden within our
bodies, playing a crucial role in the host's physiology. Several factors affect its composition …
bodies, playing a crucial role in the host's physiology. Several factors affect its composition …
Long noncoding RNAs: a missing link in osteoporosis
Osteoporosis is a systemic disease that results in loss of bone density and increased
fracture risk, particularly in the vertebrae and the hip. This condition and associated …
fracture risk, particularly in the vertebrae and the hip. This condition and associated …
[HTML][HTML] Triple culture of primary human osteoblasts, osteoclasts and osteocytes as an in vitro bone model
In vitro evaluation of bone graft materials is generally performed by analyzing the interaction
with osteoblasts or osteoblast precursors. In vitro bone models comprising different cell …
with osteoblasts or osteoblast precursors. In vitro bone models comprising different cell …
The role of miR-21 in osteoblasts–osteoclasts coupling in vitro
MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …