A survey of the 2010 quartz crystal microbalance literature
RE Speight, MA Cooper - Journal of Molecular Recognition, 2012 - Wiley Online Library
In 2010 there has again been an increase in the number of papers published involving
piezoelectric acoustic sensors, or quartz crystal microbalances (QCM), when compared to …
piezoelectric acoustic sensors, or quartz crystal microbalances (QCM), when compared to …
Protein-lipid nanohybrids as emerging platforms for drug and gene delivery: challenges and outcomes
Nanoparticulate drug delivery systems have been long used to deliver a vast range of drugs
and bioactives owing to their ability to demonstrate novel physical, chemical, and/or …
and bioactives owing to their ability to demonstrate novel physical, chemical, and/or …
Unveiling the role of surface, size, shape and defects of iron oxide nanoparticles for theranostic applications
Iron oxide nanoparticles (IONPs) are well-known contrast agents for MRI for a wide range of
sizes and shapes. Their use as theranostic agents requires a better understanding of their …
sizes and shapes. Their use as theranostic agents requires a better understanding of their …
The biological activities of protein/oleic acid complexes reside in the fatty acid
A complex formed by human α-lactalbumin (α-LA) and oleic acid (OA), named HAMLET, has
been shown to have an apoptotic activity leading to the selective death of tumor cells. In …
been shown to have an apoptotic activity leading to the selective death of tumor cells. In …
Proteins in a brave new surfactant world
DE Otzen - Current Opinion in Colloid & Interface Science, 2015 - Elsevier
This review discusses emerging topics within the field of protein–surfactant interactions over
the last 4–5 years. The application of small-angle x-ray scattering has allowed us to …
the last 4–5 years. The application of small-angle x-ray scattering has allowed us to …
Structure and function of human α‐lactalbumin made lethal to tumor cells (HAMLET)‐type complexes
AK Mossberg, K Hun Mok… - The FEBS …, 2010 - Wiley Online Library
Human α‐lactalbumin made lethal to tumor cells (HAMLET) and equine lysozyme with oleic
acid (ELOA) are complexes consisting of protein and fatty acid that exhibit cytotoxic …
acid (ELOA) are complexes consisting of protein and fatty acid that exhibit cytotoxic …
Oleic acid is a key cytotoxic component of HAMLET-like complexes
SE Permyakov, EL Knyazeva, LM Khasanova… - Biological …, 2012 - degruyter.com
HAMLET is a complex of α-lactalbumin (α-LA) with oleic acid (OA) that selectively kills tumor
cells and Streptococcus pneumoniae. To assess the contribution of the proteinaceous …
cells and Streptococcus pneumoniae. To assess the contribution of the proteinaceous …
Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes
T Nakamura, T Aizawa, R Kariya, S Okada… - Journal of Biological …, 2013 - jbc.org
Although HAMLET (human α-lactalbumin made lethal to tumor cells), a complex formed by
human α-lactalbumin and oleic acid, has a unique apoptotic activity for the selective killing of …
human α-lactalbumin and oleic acid, has a unique apoptotic activity for the selective killing of …
Protein–fatty acid complexes: biochemistry, biophysics and function
CR Brinkmann, S Thiel, DE Otzen - The FEBS journal, 2013 - Wiley Online Library
Thirteen years ago, α‐lactalbumin (α‐LA) was first reported to form a complex with oleic acid
(OA). This complex, called HAMLET (human α‐lactalbumin made lethal to tumour cells), was …
(OA). This complex, called HAMLET (human α‐lactalbumin made lethal to tumour cells), was …
[PDF][PDF] Structure and potential cellular targets of HAMLET-like anti-cancer compounds made from milk components
The HAMLET family of compounds (Human Alpha-lactalbumin Made Lethal to Tumours)
was discovered during studies on the properties of human milk, and is a class of protein-lipid …
was discovered during studies on the properties of human milk, and is a class of protein-lipid …