Oscillatory behaviors in genetic regulatory networks mediated by microRNA with time delays and reaction-diffusion terms

Y Zhang, H Liu, F Yan, J Zhou - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
In this paper, we investigate the oscillatory expression in Escherichia coli mediated by
microRNA with time delays and reaction-diffusion terms. First of all, the integrated effects of …

Transient transcription factor depletions explain diverse single-cell responses of LexA target promoters to mild DNA damage

L Galbusera, G Bellement, T Julou, E van Nimwegen - BioRxiv, 2024 - biorxiv.org
In bacteria, the effects of transcription factors (TFs) on the expression of their target genes
are highly stochastic at the single-cell level. Not only do TF concentrations fluctuate in time …

Diffusion driven oscillations in gene regulatory networks

CK Macnamara, MAJ Chaplain - Journal of Theoretical Biology, 2016 - Elsevier
Gene regulatory networks (GRNs) play an important role in maintaining cellular function by
correctly timing key processes such as cell division and apoptosis. GRNs are known to …

Oscillatory expression in Escherichia coli mediated by microRNAs with transcriptional and translational time delays

Y Zhang, H Liu, J Zhou - IET Systems Biology, 2016 - Wiley Online Library
The primary objective of this study is to study oscillatory expression of gene regulatory
network in Escherichia coli mediated by microRNAs (sRNAs) with transcriptional and …

Oscillatory behaviors of gene expression in escherichia coli by transcriptional and translational time delays

Y Zhang, H Liu, J Zhou - 2016 35th Chinese Control …, 2016 - ieeexplore.ieee.org
In the process of gene expression, time delays are unavoidable due primarily to the slow
process of transcription, translation and translocation processes. It is observed that gene …

Stress-induced hypermutation as a physical property of life, a force of natural selection and its role in four thought experiments

L Hilbert - Physical Biology, 2013 - iopscience.iop.org
The independence of genetic mutation rate from selection is central to neo-Darwinian
evolutionary theory. However, it has been continuously challenged for more than 30 years …

Kinetic aspects of enzyme-mediated repair of DNA single-strand breaks

VP Zhdanov - Biosystems, 2016 - Elsevier
In cells and bacteria, DNA can be damaged in different ways. The efficient damage repair,
mediated by various enzymes, is crucial for their survival. Most frequently, the damage is …

Математическая модель регуляторного контура Rob, MarR и MarA генной сети Escherichia coli

МТ Ри, СС Хайрулин, ОВ Сайк - Ученые записки Казанского …, 2013 - cyberleninka.ru
В работе приводятся результаты исследования математической модели,
описывающей регуляторный контур генной сети Escherichia coli, состоящей из трех …