ROS: Basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

Progress in understanding oxidative stress, aging, and aging-related diseases

J Yang, J Luo, X Tian, Y Zhao, Y Li, X Wu - Antioxidants, 2024 - mdpi.com
Under normal physiological conditions, reactive oxygen species (ROS) are produced
through redox reactions as byproducts of respiratory and metabolic activities. However, due …

Oxidative stress-mediated atherosclerosis: mechanisms and therapies

X Yang, Y Li, Y Li, X Ren, X Zhang, D Hu, Y Gao… - Frontiers in …, 2017 - frontiersin.org
Atherogenesis, the formation of atherosclerotic plaques, is a complex process that involves
several mechanisms, including endothelial dysfunction, neovascularization, vascular …

ROS signaling in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)

M Kellner, S Noonepalle, Q Lu, A Srivastava… - … redox signaling in …, 2017 - Springer
The generation of reactive oxygen species (ROS) plays an important role for the
maintenance of cellular processes and functions in the body. However, the excessive …

Nanoparticles in medicine: a focus on vascular oxidative stress

MD Mauricio, S Guerra-Ojeda… - Oxidative Medicine …, 2018 - Wiley Online Library
Nanotechnology has had a significant impact on medicine in recent years, its application
being referred to as nanomedicine. Nanoparticles have certain properties with biomedical …

[HTML][HTML] Nrf2 and heme oxygenase-1 involvement in atherosclerosis related oxidative stress

JA Alonso-Piñeiro, A Gonzalez-Rovira… - Antioxidants, 2021 - mdpi.com
Atherosclerosis remains the underlying process responsible for cardiovascular diseases
and the high mortality rates associated. This chronic inflammatory disease progresses with …

Lipid peroxidation in atherosclerotic cardiovascular diseases

E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …

Inflammaging: mechanisms and role in the cardiac and vasculature

A Ajoolabady, D Pratico, M Vinciguerra, GYH Lip… - Trends in Endocrinology …, 2023 - cell.com
Aging triggers a wide range of cellular and molecular aberrations in the body, giving rise to
inflammation and associated diseases. In particular, aging is associated with persistent low …

Mammalian NADPH oxidases

H Buvelot, V Jaquet, KH Krause - NADPH Oxidases: Methods and …, 2019 - Springer
Reactive oxygen species (ROS) are highly reactive oxygen derivatives. Initially, they were
considered as metabolic by-products (of mitochondria in particular), which consistently lead …

[HTML][HTML] NADPH oxidases and oxidative stress in the pathogenesis of atrial fibrillation

R Ramos-Mondragón, A Lozhkin, AE Vendrov… - Antioxidants, 2023 - mdpi.com
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and its prevalence
increases with age. The irregular and rapid contraction of the atria can lead to ineffective …