Hyperspectral imaging in neurosurgery: a review of systems, computational methods, and clinical applications

A Kotwal, V Saragadam, JD Bernstock… - Journal of …, 2025‏ - spiedigitallibrary.org
Significance Accurate identification between pathologic (eg, tumors) and healthy brain
tissue is a critical need in neurosurgery. However, conventional surgical adjuncts have …

Advances in translational imaging of the microcirculation

M Guerraty, A Bhargava, J Senarathna… - …, 2021‏ - Wiley Online Library
The past few decades have seen an explosion in the development and use of methods for
imaging the human microcirculation during health and disease. The confluence of …

Optimal spectral combination of a hyperspectral camera for intraoperative hemodynamic and metabolic brain map**

C Caredda, L Mahieu-Williame, R Sablong, M Sdika… - Applied Sciences, 2020‏ - mdpi.com
Intraoperative optical imaging is a localization technique for the functional areas of the
human brain cortex during neurosurgical procedures. These areas are assessed by …

[HTML][HTML] Intraoperative identification of functional brain areas with RGB imaging using statistical parametric map**: Simulation and clinical studies

C Caredda, E Van Reeth, L Mahieu-Williame… - NeuroImage, 2023‏ - Elsevier
Complementary technique to preoperative fMRI and electrical brain stimulation (EBS) for
glioma resection could improve dramatically the surgical procedure and patient care …

HyperProbe consortium: innovate tumour neurosurgery with innovative photonic solutions

L Giannoni, M Marradi, M Marchetti… - … on Biomedical Optics, 2023‏ - opg.optica.org
Recent advancements in imaging technologies (MRI, PET, CT, among others) have
significantly improved clinical localisation of lesions of the central nervous system (CNS) …

A priori free spectral unmixing with periodic absorbance changes: application for auto-calibrated intraoperative functional brain map**

C Caredda, JE Cohen, L Mahieu-Williame… - Biomedical optics …, 2023‏ - opg.optica.org
Spectral unmixing designates techniques that allow to decompose measured spectra into
linear or non-linear combination of spectra of all targets (endmembers). This technique was …

Real time intraoperative functional brain map** based on rgb imaging

C Caredda, L Mahieu-Williame, R Sablong, M Sdika… - IRBM, 2021‏ - Elsevier
Intraoperative optical imaging is a localization technique for the functional areas of the
human brain cortex during neurosurgical procedures. However, it still lacks robustness to be …

Topographic map** of the primary sensory cortex using intraoperative optical imaging and tactile irritation

WH Polanski, M Oelschlägel, TA Juratli, H Wahl… - Brain topography, 2023‏ - Springer
The determination of exact tumor boundaries within eloquent brain regions is essential to
maximize the extent of resection. Recent studies showed that intraoperative optical imaging …

Digital instrument simulator to optimize the development of hyperspectral systems: application for intraoperative functional brain map**

C Caredda, F Lange, L Giannoni… - Journal of …, 2025‏ - spiedigitallibrary.org
Significance Intraoperative optical imaging is a localization technique for the functional
areas of the human brain cortex during neurosurgical procedures. These areas can be …

Intraoperative functional and metabolic brain map** using hyperspectral imaging

C Caredda, L Mahieu-Williame… - Clinical and …, 2020‏ - spiedigitallibrary.org
The acquisition of narrow wavelength bands in the Near-Infrared (NIR) range using
hyperspectral imaging have the potential to yield functional and metabolic information …