Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …

During the past ten years, dramatic advances have been made in unraveling the biological
bases of age-related macular degeneration (AMD), the most common cause of irreversible …

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed
world. It is a complex multifactorial disease, and despite new advances in treatment, many …

The retinal pigment epithelium (RPE) comprises a monolayer of cells located between the
neuroretina and the choriocapillaries. The RPE serves several important functions in the …

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed
world. It is a multifactorial disease, and current therapy predominantly limits damage only …

Background The vitreous humor is a transparent, gelatinous mass whose main constituent is
water. It plays an important role in providing metabolic nutrient requirements of the lens …

Age-related macular degeneration (AMD) is an inflammatory disease, which causes visual
impairment and blindness in older people. The proteins of the complement system are …

To assess a potential diagnostic and therapeutic biomarker for age-related macular
degeneration (AMD), we sequenced the complement factor I gene (CFI) in 2266 individuals …

Age-related macular degeneration (AMD) is an ocular neurodegenerative disorder and is
the leading cause of legal blindness in Western societies, with a prevalence of up to 8 …

Age-related macular degeneration (AMD) is a major cause of visual impairment in the
western world. It is characterized by the presence of lipoproteinaceous deposits (drusen) in …