The emergent properties of the connected brain

M Thiebaut de Schotten, SJ Forkel - Science, 2022 - science.org
There is more to brain connections than the mere transfer of signals between brain regions.
Behavior and cognition emerge through cortical area interaction. This requires integration …

Towards a biologically annotated brain connectome

V Bazinet, JY Hansen, B Misic - Nature reviews neuroscience, 2023 - nature.com
The brain is a network of interleaved neural circuits. In modern connectomics, brain
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …

Data leakage inflates prediction performance in connectome-based machine learning models

M Rosenblatt, L Tejavibulya, R Jiang, S Noble… - Nature …, 2024 - nature.com
Predictive modeling is a central technique in neuroimaging to identify brain-behavior
relationships and test their generalizability to unseen data. However, data leakage …

Brain–phenotype models fail for individuals who defy sample stereotypes

AS Greene, X Shen, S Noble, C Horien, CA Hahn… - Nature, 2022 - nature.com
Individual differences in brain functional organization track a range of traits, symptoms and
behaviours,,,,,,,,,,–. So far, work modelling linear brain–phenotype relationships has …

Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder

MK Doss, M Považan, MD Rosenberg… - Translational …, 2021 - nature.com
Psilocybin has shown promise for the treatment of mood disorders, which are often
accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have …

Braingnn: Interpretable brain graph neural network for fmri analysis

X Li, Y Zhou, N Dvornek, M Zhang, S Gao… - Medical Image …, 2021 - Elsevier
Understanding which brain regions are related to a specific neurological disorder or
cognitive stimuli has been an important area of neuroimaging research. We propose …

Neuroimaging-based individualized prediction of cognition and behavior for mental disorders and health: methods and promises

J Sui, R Jiang, J Bustillo, V Calhoun - Biological psychiatry, 2020 - Elsevier
The neuroimaging community has witnessed a paradigm shift in biomarker discovery from
using traditional univariate brain map** approaches to multivariate predictive models …