New entity—thalassemic endocrine disease: major beta-thalassemia and endocrine involvement

M Carsote, C Vasiliu, AI Trandafir, SE Albu… - Diagnostics, 2022 - mdpi.com
Beta-thalassemia (BTH), a recessively inherited haemoglobin (Hb) disorder, causes iron
overload (IO), extra-medullary haematopoiesis and bone marrow expansion with major …

Molecular mechanisms of hematological and biochemical alterations in malaria: a review

IU Okagu, RN Aguchem, CA Ezema… - Molecular and …, 2022 - Elsevier
Malaria is a dangerous disease that contributes to millions of hospital visits and hundreds of
thousands of deaths, especially in children residing in sub-Saharan Africa. Although several …

Lipid Peroxidation in Muscle Foods: Impact on Quality, Safety and Human Health

SG Dragoev - Foods, 2024 - mdpi.com
The issue of lipid changes in muscle foods under the action of atmospheric oxygen has
captured the attention of researchers for over a century. Lipid oxidative processes initiate …

Prevalence and molecular characterization of common thalassemia among people of reproductive age in the border area of Guangxi-Yunnan-Guizhou province in …

GD Xu, CF Wang, JL Wang, M Lin, ZY Chang… - …, 2022 - Taylor & Francis
Objectives: Thalassemia, the most common global monogenetic disorder, is highly prevalent
in southern China. Epidemiological and molecular characterization of thalassemia is …

Iron in blood cells: Function, relation to disease, and potential for magnetic separation

S Barua, S Ciannella, L Tijani… - Biotechnology and …, 2023 - Wiley Online Library
Iron in blood cells has several physiological functions like transporting oxygen to cells and
maintaining iron homeostasis. Iron is primarily contained in red blood cells (RBCs), but …

Causes of Death and Mortality Trends in Individuals with Thalassemia in the United States, 1999-2020

JY Tan, YH Yeo, KH Chan, HS Shaaban… - Journal of blood …, 2024 - Taylor & Francis
Purpose Our study aims to describe the mortality trends and disparities among individuals
with thalassemia in the United States (US). Patients and Methods We used CDC WONDER …

Gene Mutation Spectrum among Alpha-Thalassaemia Patients in Northeast Peninsular Malaysia

D Vijian, WS Wan Ab Rahman, KT Ponnuraj, Z Zulkafli… - Diagnostics, 2023 - mdpi.com
(1) Background: Alpha (α)-thalassaemia is a genetic disorder that affects 5% of the world
population. Deletional or nondeletional mutations of one or both HBA1 and HBA2 on …

[HTML][HTML] Haematopoietic Stem Cell Transplantation in Thalassaemia Major: A Narrative Review

R Yousuf, D Jahan, S Sinha… - Advances in Human …, 2023 - journals.lww.com
Thalassaemia constitutes an especially prevalent human monogenic illness caused by a
lack of synthesis of the α-or β-globin chains. The clinical impact of β-thalassaemia is worse …

Alterations in Trace Elements and Cation Profiles in Transfusion-Dependent Thalassemia Patients

MAS Ridha, MK Kahlol, HK Al-Hakeim - Transfusion and Apheresis …, 2024 - Elsevier
Background Transfusion-dependent thalassemia (TDT) is a severe form of betathalassemia,
characterized by defective-globin production, resulting in a buildup of unpaired alpha globin …

[PDF][PDF] Dental Dilemmas in Blood Disorders: Navigating Oral Health in Hematological Diseases

MC Treviño-Tijerina, J Garza-Villarreal… - Int. J. Appl. Dent …, 2023 - oraljournal.com
Introduction: The circulatory system is highly complex, and any dysfunction within the blood
circulatory system can lead to blood diseases. Hemoglobinopathies are among the most …