Advances in spheroids and organoids on a chip

G Fang, YC Chen, H Lu, D ** - Advanced Functional Materials, 2023 - Wiley Online Library
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

[HTML][HTML] Patient-derived organoids in translational oncology and drug screening

R Yang, Y Yu - Cancer Letters, 2023 - Elsevier
Patient-derived organoids (PDO) are a new biomedical research model that can reconstruct
phenotypic and genetic characteristics of the original tissue and are useful for research on …

Advanced strategies for 3D bioprinting of tissue and organ analogs using alginate hydrogel bioinks

Q Gao, BS Kim, G Gao - Marine Drugs, 2021 - mdpi.com
Alginate is a natural polysaccharide that typically originates from various species of algae.
Due to its low cost, good biocompatibility, and rapid ionic gelation, the alginate hydrogel has …

Recent methods of droplet microfluidics and their applications in spheroids and organoids

Y Wang, M Liu, Y Zhang, H Liu, L Han - Lab on a Chip, 2023 - pubs.rsc.org
Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …

Marine‐derived hydrogels for biomedical applications

X Lin, J Wang, X Wu, Y Luo, Y Wang… - Advanced Functional …, 2023 - Wiley Online Library
Marine organisms provide novel and broad sources for the preparations and applications of
biomaterials. Since the urgent requirement of bio‐hydrogels to mimic tissue extracellular …

Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies

Z Zhou, Y Pang, J Ji, J He, T Liu, L Ouyang… - Nature Reviews …, 2024 - nature.com
In vitro 3D models are advanced biological tools that have been established to overcome
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …

Aqueous batteries for human body electronic devices: Focus Review

J Li, P Ruan, X Chen, S Lei, B Lu, Z Chen… - ACS Energy …, 2023 - ACS Publications
In the pursuit of convenient and healthy lives, human body electronic devices with
interactive, medical, and communication functions have been gradually developed …

Droplet-based microfluidics: Applications in pharmaceuticals

TND Trinh, HDK Do, NN Nam, TT Dan, KTL Trinh… - Pharmaceuticals, 2023 - mdpi.com
Droplet-based microfluidics offer great opportunities for applications in various fields, such
as diagnostics, food sciences, and drug discovery. A droplet provides an isolated …

Flourishing tumor organoids: History, emerging technology, and application

Q Yang, M Li, X Yang, Z **ao, X Tong… - Bioengineering & …, 2023 - Wiley Online Library
Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …

Advances in microfluidic technologies in organoid research

H Liu, Z Gan, X Qin, Y Wang… - Advanced Healthcare …, 2024 - Wiley Online Library
Organoids have emerged as major technological breakthroughs and novel organ models
that have revolutionized biomedical research by recapitulating the key structural and …