Myocardial infarction (MI) is a cardiovascular emergency and the leading cause of death
worldwide. Inflammatory and immune responses are initiated immediately after MI, leading …

Scientists are captivated by the prospect of creating a fully synthetic cell, offering the
potential to revolutionize biology, medicine and biotechnology. In this Viewpoint, a panel of …

Cells, the fundamental units of life, orchestrate intricate functions—motility, adaptation,
replication, communication, and self-organization within tissues. Originating from …

Progress in bottom-up synthetic biology has stimulated the development of synthetic cells
(SCs), autonomous protein-manufacturing particles, as dynamic biomimetics for replacing …

Biological cells display complex internal architectures with distinct micro environments that
establish the chemical heterogeneity needed to sustain cellular functions. The continued …

Life-like systems need to maintain a basal metabolism, which includes importing a variety of
building blocks required for macromolecule synthesis, exporting dead-end products, and …

Synthetic cells containing genetic programs and protein expression machinery are
increasingly recognized as powerful counterparts to engineered living cells in the context of …

Signal transduction across biological membranes is among the most important evolutionary
achievements. Herein, for the design of artificial cells, we engineer fully synthetic receptors …

Within many chemical and biological systems, both synthetic and natural, communication via
chemical messengers is widely viewed as a key feature. Often known as molecular …

Eukaryotic cells are characterized by multiple chemically distinct compartments, one of the
most notable being the nucleus. Within these compartments, there is a continuous exchange …