Beyond horizontal gene transfer: the role of plasmids in bacterial evolution
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …
accessory genes by horizontal gene transfer. However, recent studies have revealed that …
Antibiotic-resistance genes in waste water
Waste water and waste water treatment plants can act as reservoirs and environmental
suppliers of antibiotic resistance. They have also been proposed to be hotspots for …
suppliers of antibiotic resistance. They have also been proposed to be hotspots for …
Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in
the current COVID-19 pandemic. Worldwide this disease has infected over 2.5 million …
the current COVID-19 pandemic. Worldwide this disease has infected over 2.5 million …
Long-term field application of sewage sludge increases the abundance of antibiotic resistance genes in soil
Sewage sludge and manure are common soil amendments in crop production; however,
their impact on the abundance and diversity of the antibiotic resistome in soil remains …
their impact on the abundance and diversity of the antibiotic resistome in soil remains …
Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes
It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
Mobility of plasmids
Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …
They code for genes involved in many aspects of microbial biology, including detoxication …
Comparison of antibiotic-resistant bacteria and antibiotic resistance genes abundance in hospital and community wastewater: A systematic review
N Hassoun-Kheir, Y Stabholz, JU Kreft… - Science of the Total …, 2020 - Elsevier
Antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) are constantly
shed into the aquatic environment, with hospital wastewater potentially acting as an …
shed into the aquatic environment, with hospital wastewater potentially acting as an …
The ecology and evolution of pangenomes
Since the first genome-scale comparisons, it has been evident that the genomes of many
species are unbound by strict vertical descent: Large differences in gene content can occur …
species are unbound by strict vertical descent: Large differences in gene content can occur …
Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens
HW Stokes, MR Gillings - FEMS microbiology reviews, 2011 - academic.oup.com
Antibiotics were one of the great discoveries of the 20th century. However, resistance
appeared even in the earliest years of the antibiotic era. Antibiotic resistance continues to …
appeared even in the earliest years of the antibiotic era. Antibiotic resistance continues to …