Micronano Synergetic Three-Dimensional Bioelectronics: A Revolutionary Breakthrough Platform for Cardiac Electrophysiology

J Zheng, J Fang, D Xu, H Liu, X Wei, C Qin, J Xue… - ACS …, 2024 - ACS Publications
Cardiovascular diseases (CVDs) are the leading cause of mortality and therefore pose a
significant threat to human health. Cardiac electrophysiology plays a crucial role in the …

Silicon LSI-based smart stimulators for retinal prosthesis

J Ohta, T Tokuda, K Kagawa, T Furumiya… - IEEE Engineering in …, 2006 - ieeexplore.ieee.org
In this article, the authors report on a retinal prosthesis smart stimulator that is biocompatible
and fully compatible with a standard large-scale-integration (LSI) structure and that provides …

In vivo neuronal action potential recordings via three-dimensional microscale needle-electrode arrays

A Fujishiro, H Kaneko, T Kawashima, M Ishida… - Scientific Reports, 2014 - nature.com
Very fine needle-electrode arrays potentially offer both low invasiveness and high spatial
resolution of electrophysiological neuronal recordings in vivo. Herein we report the …

Single 5 μm diameter needle electrode block modules for unit recordings in vivo

H Sawahata, S Yamagiwa, A Moriya, T Dong, H Oi… - Scientific reports, 2016 - nature.com
Investigations into mechanisms in various cortical areas can be greatly improved and
supported by stable recording of single neuronal activity. In this study, fine silicon wire …

Flexible and extendible neural interface device based on cooperative multi-chip CMOS LSI architecture

T Tokuda, YL Pan, A Uehara, K Kagawa… - Sensors and Actuators A …, 2005 - Elsevier
An LSI-based cooperative multi-chip neural interface device, for stimulation as well as
recording, is proposed and fabricated. The proposed multi-chip device consists of small …

Low-invasive neural recording in mouse models with diabetes via an ultrasmall needle-electrode

R Sanda, K Yamashita, H Sawahata… - Biosensors and …, 2023 - Elsevier
Diabetes is known to cause a variety of complications, having a high correlation with
Alzheimer's disease. Electrophysiological recording using a microscale needle electrode is …

Dissolvable base scaffolds allow tissue penetration of high-aspect-ratio flexible microneedles.

S Yagi, S Yamagiwa, Y Kubota… - Advanced healthcare …, 2015 - europepmc.org
Microscale needle technology is important in electrophysiological studies, drug/chemical
delivery systems, optogenetic applications, and so on. In this study, dissolvable needle-base …

Vertically aligned silicon microwire arrays of various lengths by repeated selective vapor-liquid-solid growth of n-type silicon/n-type silicon

A Ikedo, T Kawashima, T Kawano, M Ishida - Applied Physics Letters, 2009 - pubs.aip.org
Repeated vapor-liquid-solid (VLS) growth with Au and PH 3–Si 2 H 6 mixture gas as the
growth catalyst and silicon source, respectively, was used to construct n-type silicon/n-type …

Nanoscale-Tipped High-Aspect-Ratio Vertical Microneedle Electrodes for Intracellular Recordings.

Y Kubota, H Oi, H Sawahata, A Goryu… - Small (Weinheim an …, 2016 - europepmc.org
Intracellular recording nanoscale electrode devices provide the advantages of a high spatial
resolution and high sensitivity. However, the length of nanowire/nanotube-based …

Performance improvement and functionalization of an electrode array for retinal prosthesis by iridium oxide coating and introduction of smart-wiring technology using …

T Noda, K Sasagawa, T Tokuda, Y Terasawa… - Sensors and Actuators A …, 2014 - Elsevier
The improvement of an electrode array for retinal prosthesis is described. Two elements of
fundamental technology required in next-generation retinal prosthesis, the miniaturization of …