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Pathobiology of Helicobacter pylori–induced gastric cancer
Colonization of the human stomach by Helicobacter pylori and its role in causing gastric
cancer is one of the richest examples of a complex relationship among human cells …
cancer is one of the richest examples of a complex relationship among human cells …
The impacts of H. pylori virulence factors on the development of gastroduodenal diseases
Although most H. pylori infectors are asymptomatic, some may develop serious disease,
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …
Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori
NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …
approximately 50% of the human population, but only causes overt gastric disease in a …
Helicobacter pylori Virulence Factors Exploiting Gastric Colonization and its Pathogenicity
Helicobacter pylori colonizes the gastric epithelial cells of at least half of the world's
population, and it is the strongest risk factor for develo** gastric complications like chronic …
population, and it is the strongest risk factor for develo** gastric complications like chronic …
The Helicobacter pylori cag pathogenicity island as a determinant of gastric cancer risk
Helicobacter pylori strains can be broadly classified into two groups based on whether they
contain or lack a chromosomal region known as the cag pathogenicity island (cag PAI) …
contain or lack a chromosomal region known as the cag pathogenicity island (cag PAI) …
The Spectrum of Helicobacter-Mediated Diseases
Helicobacter pylori is the leading cause of peptic ulcer disease. The infection has been
implicated in more than 75% of duodenal ulcer cases and 17% of gastric ulcer cases. H …
implicated in more than 75% of duodenal ulcer cases and 17% of gastric ulcer cases. H …
NF-κB signaling in gastric cancer
O Sokolova, M Naumann - Toxins, 2017 - mdpi.com
Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …
Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA
V Königer, L Holsten, U Harrison, B Busch, E Loell… - Nature …, 2016 - nature.com
Helicobacter pylori (Hp) strains that carry the cag type IV secretion system (cag-T4SS) to
inject the cytotoxin-associated antigen A (CagA) into host cells are associated with peptic …
inject the cytotoxin-associated antigen A (CagA) into host cells are associated with peptic …
Helicobacter pylori Virulence Factor Cytotoxin-Associated Gene A (CagA)-Mediated Gastric Pathogenicity
Helicobacter pylori causes persistent infection in the gastric epithelium of more than half of
the world's population, leading to the development of severe complications such as peptic …
the world's population, leading to the development of severe complications such as peptic …
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress
Exposure of gastric epithelial cells to the bacterial carcinogen Helicobacter pylori causes
DNA double strand breaks. Here, we show that H. pylori-induced DNA damage occurs co …
DNA double strand breaks. Here, we show that H. pylori-induced DNA damage occurs co …