Functions of S100 proteins

R Donato, BR cannon, G Sorci, F Riuzzi… - Current molecular …, 2013 - ingentaconnect.com
The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation

LJ Sparvero, D Asafu-Adjei, R Kang, D Tang… - Journal of translational …, 2009 - Springer
Abstract The Receptor for Advanced Glycation Endproducts [RAGE] is an evolutionarily
recent member of the immunoglobulin super-family, encoded in the Class III region of the …

Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway

AFK Vizuete, F Fróes, M Seady, C Zanotto… - Journal of …, 2022 - Springer
Neuroinflammation is a common feature during the development of neurological disorders
and neurodegenerative diseases, where glial cells, such as microglia and astrocytes, play …

[HTML][HTML] Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative …

D Cattani, PA Cesconetto, MK Tavares, EB Parisotto… - Toxicology, 2017 - Elsevier
We have previously demonstrated that maternal exposure to glyphosate-based herbicide
(GBH) leads to glutamate excitotoxicity in 15-day-old rat hippocampus. The present study …

Biological and methodological features of the measurement of S100B, a putative marker of brain injury

CA Gonçalves, MC Leite, P Nardin - Clinical biochemistry, 2008 - Elsevier
The S100B astroglial protein is widely used as a parameter of glial activation and/or death in
several conditions of brain injury. Cerebrospinal fluid and serum S100B variations have …

Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells

F Galland, M Seady, J Taday, SS Smaili… - Neurochemistry …, 2019 - Elsevier
The understanding of the physiology of astrocytes and their role in brain function progresses
continuously. Primary astrocyte culture is an alternative method to study these cells in an …

Green tea (−) epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia

R Biasibetti, AC Tramontina, AP Costa, MF Dutra… - Behavioural brain …, 2013 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. Intracerebroventricular
(ICV) infusion of streptozotocin (STZ) provides a relevant animal model of chronic brain …

How S100B crosses brain barriers and why it is considered a peripheral marker of brain injury

V Gayger-Dias, AFK Vizuete… - Experimental …, 2023 - journals.sagepub.com
S100B is a 21-kDa protein that is produced and secreted by astrocytes and widely used as a
marker of brain injury in clinical and experimental studies. The majority of these studies are …

S100B protein in neurodegenerative disorders

J Steiner, B Bogerts, ML Schroeter… - Clinical Chemistry and …, 2011 - degruyter.com
Abstract “Classic” neurodegenerative disorders, such as Alzheimer's disease and
amyotrophic lateral sclerosis share common pathophysiological features and involve …