Natriuretic peptides
LB Daniels, AS Maisel - Journal of the American college of cardiology, 2007 - jacc.org
Natriuretic peptides (NPs) are released from the heart in response to pressure and volume
overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important …
overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important …
Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure
Obesity has reached epidemic proportions in the United States and worldwide. Considering
the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function …
the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function …
Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population
Context Detectable levels of cardiac troponin T (cTnT) are strongly associated with structural
heart disease and increased risk of death and adverse cardiovascular events; however …
heart disease and increased risk of death and adverse cardiovascular events; however …
Cardiac remodeling in obesity
ED Abel, SE Litwin, G Sweeney - Physiological reviews, 2008 - journals.physiology.org
The dramatic increase in the prevalence of obesity and its strong association with
cardiovascular disease have resulted in unprecedented interest in understanding the effects …
cardiovascular disease have resulted in unprecedented interest in understanding the effects …
Obesity and natriuretic peptides, BNP and NT-proBNP: mechanisms and diagnostic implications for heart failure
C Madamanchi, H Alhosaini, A Sumida… - International journal of …, 2014 - Elsevier
Many advances have been made in the diagnosis and management of heart failure (HF) in
recent years. Cardiac biomarkers are an essential tool for clinicians: point of care B-type …
recent years. Cardiac biomarkers are an essential tool for clinicians: point of care B-type …
Molecular physiology of membrane guanylyl cyclase receptors
M Kuhn - Physiological reviews, 2016 - journals.physiology.org
Abstract cGMP controls many cellular functions ranging from growth, viability, and
differentiation to contractility, secretion, and ion transport. The mammalian genome encodes …
differentiation to contractility, secretion, and ion transport. The mammalian genome encodes …
Prevalence and determinants of troponin T elevation in the general population
Background—The prevalence and determinants of cardiac troponin T (cTnT) elevation in the
general population are unknown, and the significance of minimally increased cTnT remains …
general population are unknown, and the significance of minimally increased cTnT remains …
Impact of body weight and extreme obesity on the presentation, treatment, and in-hospital outcomes of 50,149 patients with ST-segment elevation myocardial …
Objectives: The aim of this study was to assess the impact of extreme (class III) obesity (body
mass index [BMI]≥ 40 kg/m2) on care and outcomes in patients with ST-segment elevation …
mass index [BMI]≥ 40 kg/m2) on care and outcomes in patients with ST-segment elevation …
B-type natriuretic peptide levels and mortality in patients with and without heart failure
MK York, DK Gupta, CF Reynolds… - Journal of the American …, 2018 - jacc.org
Background: Circulating B-type natriuretic peptide (BNP) concentrations strongly predict
mortality in patients with heart failure (HF). Both cardiac and extracardiac stimuli influence …
mortality in patients with heart failure (HF). Both cardiac and extracardiac stimuli influence …
Renin–angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: an integrated view in humans
The obesity pandemic is closely related to hypertension and metabolic syndrome. Visceral
adipose tissue plays a key role in the metabolic and cardiovascular complications of being …
adipose tissue plays a key role in the metabolic and cardiovascular complications of being …