Adult neurogenesis and “immature” neurons in mammals: an evolutionary trade-off in plasticity?
L Bonfanti, C La Rosa, M Ghibaudi… - Brain Structure and …, 2024 - Springer
Neuronal plasticity can vary remarkably in its form and degree across animal species. Adult
neurogenesis, namely the capacity to produce new neurons from neural stem cells through …
neurogenesis, namely the capacity to produce new neurons from neural stem cells through …
Unique advantages of zebrafish larvae as a model for spinal cord regeneration
SR Alper, RI Dorsky - Frontiers in molecular neuroscience, 2022 - frontiersin.org
The regenerative capacity of the spinal cord in mammals ends at birth. In contrast, teleost
fish and amphibians retain this capacity throughout life, leading to the use of the powerful …
fish and amphibians retain this capacity throughout life, leading to the use of the powerful …
[HTML][HTML] Regenerative neurogenesis: the integration of developmental, physiological and immune signals
In fishes and salamanders, but not mammals, neural stem cells switch back to neurogenesis
after injury. The signalling environment of neural stem cells is strongly altered by the …
after injury. The signalling environment of neural stem cells is strongly altered by the …
Single-cell analysis of innate spinal cord regeneration identifies intersecting modes of neuronal repair
Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we
report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of …
report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of …
A Photocaged Microtubule‐Stabilising Epothilone Allows Spatiotemporal Control of Cytoskeletal Dynamics
C Schmitt, P Mauker, NA Vepřek… - Angewandte Chemie …, 2024 - Wiley Online Library
The cytoskeleton is essential for spatial and temporal organisation of a wide range of
cellular and tissue‐level processes, such as proliferation, signalling, cargo transport …
cellular and tissue‐level processes, such as proliferation, signalling, cargo transport …
Research advances in neuroblast migration in traumatic brain injury
N Wu, W Li, Q Chen, M Chen, S Chen, C Cheng… - Molecular …, 2024 - Springer
Neuroblasts were first derived from the adult mammalian brains in the 1990s by Reynolds et
al. Since then, persistent neurogenesis in the subgranular zone (SGZ) of the hippocampus …
al. Since then, persistent neurogenesis in the subgranular zone (SGZ) of the hippocampus …
Controversies and insights into PTBP1-related astrocyte-neuron transdifferentiation: neuronal regeneration strategies for Parkinson's and Alzheimer's disease
S McDowall, V Bagda, S Hodgetts, F Mastaglia… - Translational …, 2024 - Springer
Promising therapeutic strategies are being explored to replace or regenerate the neuronal
populations that are lost in patients with neurodegenerative disorders. Several research …
populations that are lost in patients with neurodegenerative disorders. Several research …
Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish
VM Saraswathy, L Zhou, AR McAdow, B Burris… - Cell reports, 2022 - cell.com
Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in
mammals. In contrast, adult zebrafish achieve functional recovery after complete SC …
mammals. In contrast, adult zebrafish achieve functional recovery after complete SC …
Terminal differentiation precedes functional circuit integration in the peduncle neurons in regenerating Hydra vulgaris
A Escobar, S Kim, AS Primack, G Duret, CE Juliano… - Neural …, 2024 - Springer
Understanding how neural circuits are regenerated following injury is a fundamental
question in neuroscience. Hydra is a powerful model for studying this process because it …
question in neuroscience. Hydra is a powerful model for studying this process because it …
Microglia are essential for tissue contraction in wound closure after brain injury in zebrafish larvae
Wound closure after brain injury is crucial for tissue restoration but remains poorly
understood at the tissue level. We investigated this process using in vivo observations of …
understood at the tissue level. We investigated this process using in vivo observations of …