The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …

B (OCH2CF3) 3, prepared from readily available B2O3 and 2, 2, 2-trifluoroethanol, is as an
effective reagent for the direct amidation of a variety of carboxylic acids with a broad range of …

A series of 8-substituted quinolines were synthesized and tested against seizures induced
by maximal electro shock (MES), pentylenetetrazole (scMet) and antihypertensive activities …

Quinoline and its derivatives are widely studied by both synthetic and computational
chemists due to their exciting perspectives in biological and nonlinear optical (NLO) …

In this paper, we propose a combination of mean-shift-based tracking processes to establish
migrating cell trajectories through in vitro phase-contrast video microscopy. After a …

Metal-and additive-free photoredox cyclization of N-arylacrylamides is herein reported that
provides a concise access to the formation of dihydroquinolinones. In this protocol …

Several 1, 3, 4-trisubstituted pyrazole derivatives were synthesized and screened for their
cytotoxic effect in a primary 3 tumor cell line test at 10 4 M drug concentration. Compounds …

Microwave-assisted synthesis of polyheterocyclic-fused quinoline-2-thiones through the
annulation of ortho-heteroaryl anilines and CS2 was realized in water without using any …

Analysis of the methanolic extract of Calotropis procera root barks enabled the identification
of a novel cardenolide (2 ''-oxovoruscharin) to be made. Of the 27 compounds that we …

An efficient heterogeneous silver‐catalyzed α‐alkylation of nitriles and oxindoles using
alcohols via borrowing hydrogen strategy has been developed for the first time. The active …