Mesoporous silica particles as drug delivery systems—the state of the art in loading methods and the recent progress in analytical techniques for monitoring these …

K Trzeciak, A Chotera-Ouda, II Bak-Sypien… - Pharmaceutics, 2021 - mdpi.com
Conventional administration of drugs is limited by poor water solubility, low permeability,
and mediocre targeting. Safe and effective delivery of drugs and therapeutic agents remains …

Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

S Bandari, D Nyavanandi, N Dumpa… - Advanced drug delivery …, 2021 - Elsevier
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …

Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals–a comprehensive review

L Padrela, MA Rodrigues, A Duarte, AMA Dias… - Advanced drug delivery …, 2018 - Elsevier
Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Solubility, Extraction, and nanoparticles production in supercritical carbon dioxide: A mini‐review

G Sodeifian, MMB Usefi - ChemBioEng Reviews, 2023 - Wiley Online Library
Supercritical carbon dioxide (SC‐CO2) is CO2 that is stored beyond its critical point of 7.4
MPa and 31.1° C. Given the request for consumption of a green solvent for the environment …

Mechanochemistry: A green approach in the preparation of pharmaceutical cocrystals

M Solares-Briones, G Coyote-Dotor, JC Páez-Franco… - Pharmaceutics, 2021 - mdpi.com
Mechanochemistry is considered an alternative attractive greener approach to prepare
diverse molecular compounds and has become an important synthetic tool in different fields …

Production of pure drug nanocrystals and nano co-crystals by confinement methods

F Fontana, P Figueiredo, P Zhang, JT Hirvonen… - Advanced drug delivery …, 2018 - Elsevier
The use of drug nanocrystals in the drug formulation is increasing due to the large number of
poorly water-soluble drug compounds synthetized and due to the advantages brought by the …

Recent advances in pharmaceutical cocrystals: From bench to market

R Kumar Bandaru, SR Rout, G Kenguva… - Frontiers in …, 2021 - frontiersin.org
The pharmacokinetics profile of active pharmaceutical ingredients (APIs) in the solid
pharmaceutical dosage forms is largely dependent on the solid-state characteristics of the …

Thermal inkjet printing: Prospects and applications in the development of medicine

MJ Uddin, J Hassan, D Douroumis - Technologies, 2022 - mdpi.com
Over the last 10 years, inkjet printing technologies have advanced significantly and found
several applications in the pharmaceutical and biomedical sector. Thermal inkjet printing is …

Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications

S Tambe, D Jain, Y Agarwal, P Amin - Journal of Drug Delivery Science …, 2021 - Elsevier
Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …

Ball-free mechanochemistry: in situ real-time monitoring of pharmaceutical co-crystal formation by resonant acoustic mixing

AAL Michalchuk, KS Hope, SR Kennedy… - Chemical …, 2018 - pubs.rsc.org
Resonant acoustic mixing (RAM) is a new technology designed for intensive mixing of
powders that offers the capability to process powders with minimal damage to particles. This …