Abstract Purpose of Review Retinal degenerative diseases have immense socio-economic
impact. Studying animal models that recapitulate human eye pathologies aids in …

Poultry is the most abundant livestock species with over 60 billion chickens raised globally
per year. The majority of chicken are produced from commercial flocks, however many …

Apoptosis and efficient efferocytosis are integral to growth, development, and homeostasis.
The heterogeneity of these mechanisms in different cells across distinct tissues renders it …

Understanding the mechanisms triggering the initiation of retinal regeneration in amphibians
may advance the quest for prevention and treatment options for degenerating human retina …

Purpose: We previously reported a transgenic Xenopus laevis model of retinitis pigmentosa
in which tadpoles express the bovine form of P23H rhodopsin (bP23H) in rod …

Purpose.: Amphibian retinas regenerate after injury, making them ideal for studying the
mechanisms of retinal regeneration, but this leaves their value as models of retinal …

Transgenic technologies enable the manipulation and observation of circuits controlling
behavior by permitting expression of genetically encoded reporter genes in neurons …

This study evaluated the capacity of Xenopus laevis retina to regenerate photoreceptor cells
after cyclic light-mediated acute rod photoreceptor degeneration in a transgenic P23H …

Transgenic models are invaluable tools for researching retinal degenerative disease
mechanisms. However, they are time-consuming and expensive to generate and maintain …

Purpose.: To determine whether the Xenopus laevis retina is capable of regenerating
photoreceptor cells lost through apoptotic cell death in an inducible transgenic X. laevis …