Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
[HTML][HTML] Merkel cell carcinoma: epidemiology, prognosis, therapy and unmet medical needs
Merkel cell carcinoma (MCC) is a rare skin cancer that is associated with Merkel cell
polyomavirus infection in most cases. Incidence rates of MCC have increased in past …
polyomavirus infection in most cases. Incidence rates of MCC have increased in past …
Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial
Background Merkel cell carcinoma is a rare, aggressive skin cancer with poor prognosis in
patients with advanced disease. Current standard care uses various cytotoxic chemotherapy …
patients with advanced disease. Current standard care uses various cytotoxic chemotherapy …
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …
advanced age and immunosuppression. Over the past decade, an association has been …
The distinctive mutational spectra of polyomavirus-negative Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous neuroendocrine
tumor. Merkel cell polyomavirus (MCPyV) may contribute to tumorigenesis in a subset of …
tumor. Merkel cell polyomavirus (MCPyV) may contribute to tumorigenesis in a subset of …
Viral infections
JC Sterling - Rook's Textbook of Dermatology, Ninth Edition, 2016 - Wiley Online Library
Skin disease due to viruses may be a primary infection of the epidermis or may arise
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …
PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus, and overall survival
Merkel cell carcinoma (MCC) is a lethal, virus-associated cancer that lacks effective
therapies for advanced disease. Agents blocking the PD-1/PD-L1 pathway have shown …
therapies for advanced disease. Agents blocking the PD-1/PD-L1 pathway have shown …
[HTML][HTML] Polyomavirus-negative Merkel cell carcinoma: a more aggressive subtype based on analysis of 282 cases using multimodal tumor virus detection
Previous studies have reached conflicting conclusions regarding the proportion of Merkel
cell carcinomas (MCCs) that contain the Merkel cell polyomavirus (MCPyV) and the clinical …
cell carcinomas (MCCs) that contain the Merkel cell polyomavirus (MCPyV) and the clinical …
[HTML][HTML] Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guideline
Merkel cell carcinoma (MCC) is a rare tumour of the skin of neuro-endocrine origin probably
develo** from neuronal mechanoreceptors. A collaborative group of multidisciplinary …
develo** from neuronal mechanoreceptors. A collaborative group of multidisciplinary …
A cornucopia of human polyomaviruses
During the past 6 years, focused virus hunting has led to the discovery of nine new human
polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell …
polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell …