Emerging evidence points to a strong association between the gut microbiota and the risk,
development and progression of gastrointestinal cancers such as colorectal cancer (CRC) …

Carotenoids retain plenty of health benefits and attracting much attention recently, but they
have less resistance to processing stresses, easily oxidized and chemically unstable …

Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

This work provides an elaborate characterization of human intestinal fluids (HIF) collected in
fasted-and fed-state conditions. HIF from 20 healthy volunteers (10 M/F) were aspirated by …

Over the last decade, fruit juice consumption has increased. Their rise in popularity can be
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …

This review summarizes the current knowledge on anatomy and physiology of the human
gastrointestinal tract in comparison with that of common laboratory animals (dog, pig, rat and …

Preformulation measurements are used to estimate the fraction absorbed in vivo for orally
administered compounds and thereby allow an early evaluation of the need for enabling …

Bile salts are ionic amphiphilic compounds with a steroid skeleton. Among the most
important physiological properties of bile salts are lipid transport by solubilization and …

The objective of this study was to understand quantitatively the role that bile salts play in the
digestion of emulsified lipids. The behaviours of digestion by pancreatin (1.6 mg/mL) of …