Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that
is influenced by both genetic and environmental factors. For many years, knowledge of the …

Introduction Genome‐wide association studies have led to numerous genetic loci
associated with Alzheimer's disease (AD). Whole‐genome sequencing (WGS) now permits …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare, irreversible, and progressive disease
of the lungs. Common genetic variants, in addition to nongenetic factors, have been …

Genome-wide association studies have identified common variants associated with chronic
obstructive pulmonary disease (COPD). Whole-genome sequencing (WGS) offers …

Motivation Analysis of rare variants in family-based studies remains a challenge.
Transmission-based approaches provide robustness against population stratification, but …

Background Asthma is a common respiratory disorder with a highly heterogeneous nature
that remains poorly understood. The objective was to use whole genome sequencing (WGS) …

< jats: p> By organically combining principal component analysis, spatial autocorrelation
algorithm and two-dimensional graph theory clustering algorithm, the comprehensive …

In order to better realize the design of ecological land consolidation planning and regulation
mode, the author proposes a method based on a spatial clustering algorithm. Based on GIS …

For family‐based association studies, Horvath et al. proposed an algorithm for the
association analysis between haplotypes and arbitrary phenotypes when the phase of the …

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that is
characterized by the involvement of rare genetic variants. Disease association of single rare …