Conventional cancer therapies suffer from severe off-target effects because most of them
target critical facets of cells that are generally shared by all rapidly proliferating cells. The …

While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Tumor cells metabolize in distinct pathways compared with most normal tissue cells. The
resulting tumor microenvironment would provide characteristic physiochemical conditions …

The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Systems and methods are disclosed for communicating data in an integrated sensor network
having one or more nodes coupled to an optical sensor network and a radio frequency …

Chaos and the natural evolution of tumor systems can lead to the failure of tumor therapies.
Herein, we demonstrate that iridium oxide nanoparticles (IrOx) possess acid‐activated …

The current study paves the way for improved chemotherapy by creating pH-responsive
nanogels (NGs)(GC1 and GC2) loaded with synthetic ruthenium (II) arene complexes to …

Single-chain polymer nanoparticles (SCNPs) are a well-defined and uniquely sized class of
polymer nanoparticles. The advances in polymer science over the past decades have …

Cancer cells of diverse origins express extracellular tumor-specific carbohydrate antigens
(TACAs) because of aberrant glycosylation. Overexpressed TACAs on the surface of tumor …