Mitochondria, often referred to as the powerhouses of cells, are vital organelles that are
present in almost all eukaryotic organisms, including humans. They are the key energy …

Bacterial toxins represent a vast reservoir of biochemical diversity that can be repurposed for
biomedical applications. Such proteins include a group of predicted interbacterial toxins of …

Mitochondria are central hubs for cellular metabolism, coordinating a variety of metabolic
reactions crucial for human health. Mitochondria provide most of the cellular energy via their …

Neuroinflammation plays a significant role in ischemic injury, which can be promoted by
oxidized mitochondrial DNA (Ox-mtDNA). Cytidine/uridine monophosphate kinase 2 …

Mitochondria are peculiar organelles whose proper function depends on the crosstalk
between two genomes, mitochondrial and nuclear. The human mitochondrial genome …

Although the mammalian mtDNA transcription machinery is simple and resembles
bacteriophage systems, there are many reports that nuclear transcription regulators, as …

The T-2 toxin is a highly toxic trichothecene mycotoxin that would cause serious toxicity in
humans and animals. Recent studies suggest that the central nervous system (CNS) is …

RNA decay is a key element of mitochondrial RNA metabolism. To date, the only well-
documented machinery that plays a role in mtRNA decay in humans is the complex of …

Complexome profiling (CP) is a powerful tool for systematic investigation of protein
interactors that has been primarily applied to study the composition and dynamics of …

A stop codon within the mRNA facilitates coordinated termination of protein synthesis,
releasing the nascent polypeptide from the ribosome. This essential step in gene expression …