Influence of particle properties on powder bulk behaviour and processability

UV Shah, V Karde, C Ghoroi, JYY Heng - International journal of …, 2017 - Elsevier
Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

Enhanced understanding of pharmaceutical materials through advanced characterisation and analysis

AP Ferreira, JF Gamble, MM Leane, H Park… - Aaps Pharmscitech, 2018 - Springer
The impact of pharmaceutical materials properties on drug product quality and
manufacturability is well recognised by the industry. An ongoing effort across industry and …

Effect of milling temperatures on surface area, surface energy and cohesion of pharmaceutical powders

UV Shah, Z Wang, D Olusanmi, AS Narang… - International journal of …, 2015 - Elsevier
Particle bulk and surface properties are influenced by the powder processing routes. This
study demonstrates the effect of milling temperatures on the particle surface properties …

Influence of temperature on the packing dynamics of polymer powders

G Lumay, F Francqui, C Detrembleur… - Advanced Powder …, 2020 - Elsevier
Temperature influences drastically the physical properties of polymer powders. In the
present study, the packing dynamics of polymer powders has been investigated with a …

Breakage assessment of lath-like crystals in a novel laboratory-scale agitated filter bed dryer

WP Goh, K Sinha, NK Nere, R Ho, S Bordawekar… - Pharmaceutical …, 2022 - Springer
Agitated filter bed dryer is often the equipment of choice in the pharmaceutical industry for
the isolation of potent active pharmaceutical ingredients (API) from the mother liquor and …

Strategies to Overcome Undesired Physicochemical Changes in Particle Engineering for Inhalation

M Romero-Gonzalez, J Crowther… - KONA Powder and …, 2024 - jstage.jst.go.jp
Particle engineering broadly refers to the controlled production of drug particles optimized
for size, morphology, and structure. It encompasses both destructive (top-down) and …

A method for grindability testing using the Scirocco disperser

T Bonakdar, M Ali, S Dogbe, M Ghadiri… - International Journal of …, 2016 - Elsevier
In the early stages of development of a new Active Pharmaceutical Ingredient (API),
insufficient material quantity is available for addressing processing issues, and it is highly …

Predictive Milling of Active Pharmaceutical Ingredients and Excipients

SC Dogbe - 2016 - etheses.whiterose.ac.uk
Spiral jet milling is a size reduction process used in various industries, ranging from paints to
food and pharmaceuticals. It has great benefit in the pharmaceutical industry due to its ability …

Assessment of impact breakage of carbamazepine dihydrate due to aerodynamic dispersion

WP Goh, M Ali, K Sinha, NK Nere, R Ho… - International Journal of …, 2019 - Elsevier
Acicular crystals are very common in pharmaceutical manufacturing. They are very prone to
breakage, causing unwanted particle size degradation and problems such as segregation …

Impact breakage of acicular crystals

S Saifoori, WP Goh, M Ali, M Ghadiri - Powder Technology, 2020 - Elsevier
Acicular crystals are frequently encountered in pharmaceutical and fine chemical industries.
They are prone to breakage, as a result of which their bulk behaviour changes drastically. It …