Systems neuroscience of natural behaviors in rodents

EJ Dennis, A El Hady, A Michaiel… - Journal of …, 2021 - Soc Neuroscience
Animals evolved in complex environments, producing a wide range of behaviors, including
navigation, foraging, prey capture, and conspecific interactions, which vary over timescales …

A comparison of neuroelectrophysiology databases

P Subash, A Gray, M Boswell, SL Cohen, R Garner… - Scientific Data, 2023 - nature.com
As data sharing has become more prevalent, three pillars-archives, standards, and analysis
tools-have emerged as critical components in facilitating effective data sharing and …

SpikeInterface, a unified framework for spike sorting

AP Buccino, CL Hurwitz, S Garcia, J Magland… - Elife, 2020 - elifesciences.org
Much development has been directed toward improving the performance and automation of
spike sorting. This continuous development, while essential, has contributed to an over …

[HTML][HTML] CellExplorer: A framework for visualizing and characterizing single neurons

PC Petersen, JH Siegle, NA Steinmetz, S Mahallati… - Neuron, 2021 - cell.com
The large diversity of neuron types provides the means by which cortical circuits perform
complex operations. Neuron can be described by biophysical and molecular characteristics …

Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning

F Najafi, GF Elsayed, R Cao, E Pnevmatikakis… - Neuron, 2020 - cell.com
Inhibitory neurons, which play a critical role in decision-making models, are often simplified
as a single pool of non-selective neurons lacking connection specificity. This assumption is …

Reconciling functional differences in populations of neurons recorded with two-photon imaging and electrophysiology

JH Siegle, P Ledochowitsch, X Jia, DJ Millman… - Elife, 2021 - elifesciences.org
Extracellular electrophysiology and two-photon calcium imaging are widely used methods
for measuring physiological activity with single-cell resolution across large populations of …

Dataset of human-single neuron activity during a Sternberg working memory task

M Kyzar, J Kamiński, A Brzezicka, CM Reed, JM Chung… - Scientific Data, 2024 - nature.com
We present a dataset of 1809 single neurons recorded from the human medial temporal
lobe (amygdala and hippocampus) and medial frontal lobe (anterior cingulate cortex, pre …

Brain Modeling ToolKit: An open source software suite for multiscale modeling of brain circuits

K Dai, SL Gratiy, YN Billeh, R Xu, B Cai… - PLOS Computational …, 2020 - journals.plos.org
Experimental studies in neuroscience are producing data at a rapidly increasing rate,
providing exciting opportunities and formidable challenges to existing theoretical and …

Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

BR Lee, A Budzillo, K Hadley, JA Miller, T Jarsky… - Elife, 2021 - elifesciences.org
The Patch-seq approach is a powerful variation of the patch-clamp technique that allows for
the combined electrophysiological, morphological, and transcriptomic characterization of …

Learning from unexpected events in the neocortical microcircuit

CJ Gillon, JE Pina, JA Lecoq, R Ahmed, YN Billeh… - BioRxiv, 2021 - biorxiv.org
Scientists have long conjectured that the neocortex learns the structure of the environment in
a predictive, hierarchical manner. To do so, expected, predictable features are differentiated …