Profiles of radioresistance mechanisms in prostate cancer
L Chaiswing, HL Weiss, RD Jayswal… - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Radiation therapy (RT) is commonly used for the treatment of localized prostate cancer
(PCa). However, cancer cells often develop resistance to radiation through unknown …
(PCa). However, cancer cells often develop resistance to radiation through unknown …
Modeling photoionization of aqueous DNA and its components
E Pluharova, P Slavicek… - Accounts of Chemical …, 2015 - ACS Publications
Conspectus Radiation damage to DNA is usually considered in terms of UVA and UVB
radiation. These ultraviolet rays, which are part of the solar spectrum, can indeed cause …
radiation. These ultraviolet rays, which are part of the solar spectrum, can indeed cause …
Unravelling the role of an aqueous environment on the electronic structure and ionization of phenol using photoelectron spectroscopy
JW Riley, B Wang, JL Woodhouse… - The Journal of …, 2018 - ACS Publications
Water is the predominant medium for chemistry and biology, yet its role in determining how
molecules respond to ultraviolet light is not well understood at the molecular level. Here, we …
molecules respond to ultraviolet light is not well understood at the molecular level. Here, we …
Redox properties of native and damaged DNA from mixed quantum mechanical/molecular mechanics molecular dynamics simulations
P Diamantis, I Tavernelli… - Journal of chemical …, 2020 - ACS Publications
The redox properties of two large DNA fragments composed of 39 base pairs, differing only
by an 8-oxoguanine (8oxoG) defect replacing a guanine (G), were investigated in …
by an 8-oxoguanine (8oxoG) defect replacing a guanine (G), were investigated in …
One-electron oxidation of ds (5′-GGG-3′) and ds (5′-G (8OG) G-3′) and the nature of hole distribution: A density functional theory (DFT) study
Of particular interest in radiation-induced charge transfer processes in DNA is the extent of
hole localization immediately after ionization and subsequent relaxation. To address this, we …
hole localization immediately after ionization and subsequent relaxation. To address this, we …
Damage Induced to DNA and Its Constituents by 0–3 eV UV Photoelectrons†
C Liu, Y Zheng, L Sanche - Photochemistry and Photobiology, 2022 - Wiley Online Library
The complex physical and chemical interactions between DNA and 0–3 eV electrons
released by UV photoionization can lead to the formation of various lesions such as base …
released by UV photoionization can lead to the formation of various lesions such as base …
Redox-based defect detection in packed DNA: insights from hybrid quantum mechanical/molecular mechanics molecular dynamics simulations
M Kılıç, P Diamantis, SK Johnson, O Toth… - Journal of Chemical …, 2023 - ACS Publications
The impact of an 8-oxoguanine (8oxoG) defect on the redox properties of DNA within the
nucleosome core particle (NCP) was investigated employing hybrid quantum …
nucleosome core particle (NCP) was investigated employing hybrid quantum …
Vertical ionization energies and electron affinities of native and damaged DNA bases, nucleotides, and pairs from density functional theory calculations: Model …
P Diamantis, I Tavernelli… - Journal of chemical …, 2019 - ACS Publications
To assess the effect of an 8-oxoguanine (8OG) defect base on the vertical ionization
energies (VIEs) and electron affinities (VEAs) of DNA, density functional theory calculations …
energies (VIEs) and electron affinities (VEAs) of DNA, density functional theory calculations …
Effects of BPQ binding on the nonadiabatic dynamics of excited electrons in poly (dG)–poly (dC) DNA under proton irradiation
Z Hu, ZY Deng, HJ Feng - Physical Chemistry Chemical Physics, 2024 - pubs.rsc.org
The interaction between DNA and small molecules is important for understanding the
mechanisms of DNA-based multifunctional devices and has been extensively studied …
mechanisms of DNA-based multifunctional devices and has been extensively studied …
Excited-state deactivation in 8-oxo-deoxyguanosine: comparison between anionic and neutral forms
D Tuna, W Domcke - Physical Chemistry Chemical Physics, 2016 - pubs.rsc.org
8-Oxoguanine is the most abundant oxidation product found in oxidatively damaged DNA.
The study of the excited-state properties of the corresponding deoxyribonucleoside 8-oxo …
The study of the excited-state properties of the corresponding deoxyribonucleoside 8-oxo …