Wound healing occurs as a response to disruption of the epidermis and dermis. It is an
intricate and well-orchestrated response with the goal to restore skin integrity and function …

Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Recent years have seen a marked increase in our understanding of innate lymphoid cells
(ILCs). ILCs can be classified into different groups based on their similarity to T cell subsets …

The skin is the outermost barrier of the organism that ensures protection from external harm.
Lately, our view of the skin has evolved from an inert mechanical barrier to an active organ …

Tissue-resident innate lymphoid cells (ILCs) help sustain barrier function and respond to
local signals. ILCs are traditionally classified as ILC1, ILC2 or ILC3 on the basis of their …

MAIT cells are an unconventional T cell population that can be activated through both TCR-
dependent and TCR-independent mechanisms. Here, we examined the impact of …

Tumors poorly infiltrated by T cells are more resistant to immunogenic chemotherapies and
checkpoint inhibition than highly infiltrated tumors. Using murine models, we found that …

Tissue healing and regeneration is a complex, choreographed, spatiotemporal process
involving a plethora of cell types, the activity of which is stringently regulated in order for …

Group 3 innate lymphoid cells (ILC 3), defined by expression of the transcription factor
retinoid‐related orphan receptor γt, play key roles in the regulation of inflammation and …