Th17 cells play an important role in the abnormal immune response in inflammatory bowel
disease (IBD) and are involved in the development and progression of inflammation and …

Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Intestinal fibrosis, a severe complication of Crohn's disease (CD), is characterized by
excessive extracellular matrix (ECM) deposition and induces intestinal strictures, but there …

Despite the great progress of current bacterially based biotherapeutics, their unsatisfying
efficacy and underlying safety problems have limited their clinical application. Herein …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease involving mainly the
colorectal mucosa and submucosa, the incidence of which has been on the rise in recent …

The human microbiome orchestrates a variety of metabolic, immunological and regulatory
functions in health and disease. However, experimentally dissecting host–microbiome …

Background In Crohn disease, differentiation between active intestinal inflammation and
fibrosis has implications for treatment, but current imaging modalities are not reliably …

Inflammatory bowel disease (IBD) is a chronic and idiopathic condition that results in
inflammation of the gastrointestinal tract, leading to conditions such as ulcerative colitis and …

Oxidative stress (OS) is a key factor in the generation of various pathophysiological
conditions. Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) is a major transcriptional …