Chemotherapeutic drug-induced immunogenic cell death for nanomedicine-based cancer chemo–immunotherapy
M Jiang, J Zeng, L Zhao, M Zhang, J Ma, X Guan… - Nanoscale, 2021 - pubs.rsc.org
Chemotherapy has been a conventional paradigm for cancer treatment, and multifarious
chemotherapeutic drugs have been widely employed for decades with significant …
chemotherapeutic drugs have been widely employed for decades with significant …
Inflammation in epileptogenesis after traumatic brain injury
Background Epilepsy is a common and debilitating consequence of traumatic brain injury
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …
The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
Review of recent advances on post-translational modifications that determine the role of
HMGB1 as a cytokine mediator. HMGB1 is a ubiquitous nuclear protein present in almost all …
HMGB1 as a cytokine mediator. HMGB1 is a ubiquitous nuclear protein present in almost all …
Technologies for enhanced efficacy of DNA vaccines
F Saade, N Petrovsky - Expert review of vaccines, 2012 - Taylor & Francis
Despite many years of research, human DNA vaccines have yet to fulfill their early promise.
Over the past 15 years, multiple generations of DNA vaccines have been developed and …
Over the past 15 years, multiple generations of DNA vaccines have been developed and …
Modulation of toll-like receptor signaling by antimicrobial peptides
Antimicrobial peptides (AMPs) are typically thought of as molecular hole punchers that
directly kill pathogens by membrane permeation. However, recent work has shown that …
directly kill pathogens by membrane permeation. However, recent work has shown that …
HMGB1 in systemic lupus erythematosus
T Liu, M Son, B Diamond - Frontiers in immunology, 2020 - frontiersin.org
The high-mobility group box 1 (HMGB1) has been shown to exert proinflammatory effects on
many cells of the innate immune system. Originally identified as a nuclear protein, HMGB1 …
many cells of the innate immune system. Originally identified as a nuclear protein, HMGB1 …
A pharmacoproteomic landscape of organotypic intervention responses in Gram-negative sepsis
Sepsis is the major cause of mortality across intensive care units globally, yet details of
accompanying pathological molecular events remain unclear. This knowledge gap has …
accompanying pathological molecular events remain unclear. This knowledge gap has …
Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation
K Komai, T Shichita, M Ito, M Kanamori… - International …, 2017 - academic.oup.com
Damage-associated molecular patterns (DAMPs) have been implicated in sterile
inflammation in various tissue injuries. High-mobility group box 1 (HMGB1) is a …
inflammation in various tissue injuries. High-mobility group box 1 (HMGB1) is a …
Intracellular nucleic acid sensors and autoimmunity
AN Theofilopoulos, DH Kono, B Beutler… - Journal of Interferon & …, 2011 - liebertpub.com
A collection of molecular sensors has been defined by studies in the last decade that can
recognize a diverse array of pathogens and initiate protective immune and inflammatory …
recognize a diverse array of pathogens and initiate protective immune and inflammatory …
Proteome changes in the small intestinal mucosa of broilers (Gallus gallus) induced by high concentrations of atmospheric ammonia
J Zhang, C Li, X Tang, Q Lu, R Sa, H Zhang - Proteome science, 2015 - Springer
Background Ammonia is a well-known toxicant both existing in atmospheric and aquatic
system. So far, most studies of ammonia toxicity focused on mammals or aquatic animals …
system. So far, most studies of ammonia toxicity focused on mammals or aquatic animals …