Aims Statin intolerance (SI) represents a significant public health problem for which precise
estimates of prevalence are needed. Statin intolerance remains an important clinical …

OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Background The proprotein convertase subtilisin kexin type-9 inhibitor evolocumab
produced coronary atheroma regression in statin-treated patients. Objectives The purpose of …

Importance Coronary plaques that are prone to rupture and cause adverse cardiac events
are characterized by large plaque burden, large lipid content, and thin fibrous caps. Statins …

Statins represent the cornerstone of pharmacotherapy for the prevention of atherosclerotic
cardiovascular disease. These medications not only reduce low-density lipoprotein …

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban
and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a …

Acute coronary syndromes (ACS) are a comprehensive disease concept characterized by
acute myocardial ischemia caused by disruption of coronary artery plaque and consequent …

Aims To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs)
cause atherosclerotic cardiovascular disease (ASCVD). Methods and results We assessed …

People who maintain ideal cardiovascular heath have a low lifetime risk of cardiovascular
disease. Therefore, encouraging people to achieve ideal cardiovascular health represents …

Over the last 3 decades there have been substantial improvements in treatments aimed at
reducing cardiovascular (CV) events. As these treatments have been developed, there have …