Azithromycin in viral infections

ME Oliver, TSC Hinks - Reviews in medical virology, 2021 - Wiley Online Library
Azithromycin (AZM) is a synthetic macrolide antibiotic effective against a broad range of
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …

Azithromycin: mechanisms of action and their relevance for clinical applications

MJ Parnham, VE Haber… - Pharmacology & …, 2014 - Elsevier
Azithromycin is a macrolide antibiotic which inhibits bacterial protein synthesis, quorum-
sensing and reduces the formation of biofilm. Accumulating effectively in cells, particularly …

Periodontitis: a host‐mediated disruption of microbial homeostasis. Unlearning learned concepts

PM Bartold, TE Van Dyke - Periodontology 2000, 2013 - Wiley Online Library
New concepts evolve when existing ones fail to address known factors adequately or are
invalidated by new evidence. For decades periodontitis has been considered to be caused …

LPS-induced cytokine production in human monocytes and macrophages

M Rossol, H Heine, U Meusch, D Quandt… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Lipopolysaccharide (LPS) from Gram-negative bacteria is one of the most potent innate
immune-activating stimuli known. Here we review the current understanding of LPS effects …

The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction

G Geerling, J Tauber, C Baudouin… - … & visual science, 2011 - iovs.arvojournals.org
The goals of the subcommittee were to review the current practice and published evidence
of medical and surgical treatment options for meibomian gland dysfunction (MGD) and to …

Host modulation therapy with anti‐inflammatory agents

PM Preshaw - Periodontology 2000, 2018 - Wiley Online Library
Host modulation therapy refers to a treatment concept in which drug therapies are used as
an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the …

Nonantimicrobial actions of macrolides: overview and perspectives for future development

JA Kricker, CP Page, FR Gardarsson… - Pharmacological …, 2021 - Elsevier
Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …

Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review

SM Law, RD Gray - Journal of inflammation, 2017 - Springer
Abstract Background Cystic Fibrosis (CF) is a devastating genetic disease characterised
primarily by unrelenting lung inflammation and infection resulting in premature death and …

Pathogen‐and host‐directed anti‐inflammatory activities of macrolide antibiotics

HC Steel, AJ Theron, R Cockeran… - Mediators of …, 2012 - Wiley Online Library
Macrolide antibiotics possess several, beneficial, secondary properties which complement
their primary antimicrobial activity. In addition to high levels of tissue penetration, which may …

Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype

D Amantea, M Certo, F Petrelli, C Tassorelli… - Experimental …, 2016 - Elsevier
To develop novel and effective treatments for ischemic stroke, we investigated the
neuroprotective effects of the macrolide antibiotic azithromycin in a mouse model system of …