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Azithromycin in viral infections
ME Oliver, TSC Hinks - Reviews in medical virology, 2021 - Wiley Online Library
Azithromycin (AZM) is a synthetic macrolide antibiotic effective against a broad range of
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …
Azithromycin: mechanisms of action and their relevance for clinical applications
Azithromycin is a macrolide antibiotic which inhibits bacterial protein synthesis, quorum-
sensing and reduces the formation of biofilm. Accumulating effectively in cells, particularly …
sensing and reduces the formation of biofilm. Accumulating effectively in cells, particularly …
Periodontitis: a host‐mediated disruption of microbial homeostasis. Unlearning learned concepts
PM Bartold, TE Van Dyke - Periodontology 2000, 2013 - Wiley Online Library
New concepts evolve when existing ones fail to address known factors adequately or are
invalidated by new evidence. For decades periodontitis has been considered to be caused …
invalidated by new evidence. For decades periodontitis has been considered to be caused …
LPS-induced cytokine production in human monocytes and macrophages
Lipopolysaccharide (LPS) from Gram-negative bacteria is one of the most potent innate
immune-activating stimuli known. Here we review the current understanding of LPS effects …
immune-activating stimuli known. Here we review the current understanding of LPS effects …
The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction
G Geerling, J Tauber, C Baudouin… - … & visual science, 2011 - iovs.arvojournals.org
The goals of the subcommittee were to review the current practice and published evidence
of medical and surgical treatment options for meibomian gland dysfunction (MGD) and to …
of medical and surgical treatment options for meibomian gland dysfunction (MGD) and to …
Host modulation therapy with anti‐inflammatory agents
PM Preshaw - Periodontology 2000, 2018 - Wiley Online Library
Host modulation therapy refers to a treatment concept in which drug therapies are used as
an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the …
an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the …
Nonantimicrobial actions of macrolides: overview and perspectives for future development
JA Kricker, CP Page, FR Gardarsson… - Pharmacological …, 2021 - Elsevier
Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …
Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review
SM Law, RD Gray - Journal of inflammation, 2017 - Springer
Abstract Background Cystic Fibrosis (CF) is a devastating genetic disease characterised
primarily by unrelenting lung inflammation and infection resulting in premature death and …
primarily by unrelenting lung inflammation and infection resulting in premature death and …
Pathogen‐and host‐directed anti‐inflammatory activities of macrolide antibiotics
HC Steel, AJ Theron, R Cockeran… - Mediators of …, 2012 - Wiley Online Library
Macrolide antibiotics possess several, beneficial, secondary properties which complement
their primary antimicrobial activity. In addition to high levels of tissue penetration, which may …
their primary antimicrobial activity. In addition to high levels of tissue penetration, which may …
Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype
To develop novel and effective treatments for ischemic stroke, we investigated the
neuroprotective effects of the macrolide antibiotic azithromycin in a mouse model system of …
neuroprotective effects of the macrolide antibiotic azithromycin in a mouse model system of …