Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

To combat the threat to human health and biosecurity from antimicrobial resistance, an
understanding of its mechanisms and drivers is needed. Emergence of antimicrobial …

The causes of antibiotic resistance are complex and include human behaviour at many
levels of society; the consequences affect everybody in the world. Similarities with climate …

The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

Quinolone and fluoroquinolone antibiotics are potent, broad-spectrum agents commonly
used to treat a range of infections. Resistance to these agents is multifactorial and can be via …

Rapid molecular ty** of bacterial pathogens is critical for public health epidemiology,
surveillance and infection control, yet routine use of whole genome sequencing (WGS) for …

Among the human health conditions linked to microbial communities, phenotypes are often
associated with only a subset of strains within causal microbial groups. Although it has been …

Recombination is an important evolutionary force in bacteria, but it remains challenging to
reconstruct the imports that occurred in the ancestry of a genomic sample. Here we present …

Antimicrobial resistance (AMR) in humans is inter-linked with AMR in other populations,
especially farm animals, and in the wider environment. The relatively few bacterial species …

Multilocus sequence ty** (MLST) was proposed in 1998 as a portable sequence-based
method for identifying clonal relationships among bacteria. Today, in the whole-genome era …