Molecular and cellular heterogeneity in rheumatoid arthritis: mechanisms and clinical implications
Rheumatoid arthritis is an autoimmune disease that exhibits significant clinical
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …
Monocytes in rheumatoid arthritis: Circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis
AK Rana, Y Li, Q Dang, F Yang - International immunopharmacology, 2018 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic, autoimmune and inflammatory disease
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …
Interleukin 33 is a guardian of barriers and a local alarmin
NT Martin, MU Martin - Nature immunology, 2016 - nature.com
Abstract Interleukin 33 (IL-33) is a member of the IL-1 family of cytokines with a growing
number of target cells and a plethora of biological functions. Although it has commonalities …
number of target cells and a plethora of biological functions. Although it has commonalities …
Bystander activation and autoimmunity
The interaction over time of genetic, epigenetic and environmental factors (ie, autoimmune
ecology) increases or decreases the liability an individual would have to develop an …
ecology) increases or decreases the liability an individual would have to develop an …
IL‐33: biological properties, functions, and roles in airway disease
LY Drake, H Kita - Immunological reviews, 2017 - Wiley Online Library
Summary Interleukin (IL)‐33 is a key cytokine involved in type 2 immunity and allergic
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …
IL-33, an alarmin of the IL-1 family involved in allergic and non allergic inflammation: focus on the mechanisms of regulation of its activity
C Cayrol - Cells, 2021 - mdpi.com
Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) family that is expressed in the
nuclei of endothelial and epithelial cells of barrier tissues, among others. It functions as an …
nuclei of endothelial and epithelial cells of barrier tissues, among others. It functions as an …
How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis?
PM Preshaw, JJ Taylor - Journal of clinical periodontology, 2011 - Wiley Online Library
Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …
The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB–stimulated gene transcription
S Ali, A Mohs, M Thomas, J Klare, R Ross… - The Journal of …, 2011 - journals.aai.org
Full-length IL-33 is a member of the IL-1 family of cytokines, which can act in an autocrine or
paracrine manner by binding to the IL-33R on several different target cell types. In addition …
paracrine manner by binding to the IL-33R on several different target cell types. In addition …
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization
The contribution of mast cells in the microenvironment of solid malignancies remains
controversial. Here we functionally assess the impact of tumor-adjacent, submucosal mast …
controversial. Here we functionally assess the impact of tumor-adjacent, submucosal mast …
[HTML][HTML] Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature
S Demyanets, C Kaun, R Pentz, KA Krychtiuk… - Journal of molecular and …, 2013 - Elsevier
Interleukin-33 (IL-33) is a recently described member of the IL-1 family of cytokines, which
was identified as a ligand for the ST2 receptor. Components of the IL-33/ST2 system were …
was identified as a ligand for the ST2 receptor. Components of the IL-33/ST2 system were …