Small-molecule fluorescent probes for binding-and activity-based sensing of redox-active biological metals

K Grover, A Koblova, AT Pezacki, CJ Chang… - Chemical …, 2024 - ACS Publications
Although transition metals constitute less than 0.1% of the total mass within a human body,
they have a substantial impact on fundamental biological processes across all kingdoms of …

[HTML][HTML] New antimicrobial strategies based on metal complexes

M Claudel, JV Schwarte, KM Fromm - Chemistry, 2020 - mdpi.com
Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

I Yousuf, M Bashir, F Arjmand, S Tabassum - Coordination Chemistry …, 2021 - Elsevier
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …

Advances in cobalt complexes as anticancer agents

CR Munteanu, K Suntharalingam - Dalton Transactions, 2015 - pubs.rsc.org
The evolution of resistance to traditional platinum-based anticancer drugs has compelled
researchers to investigate the cytostatic properties of alternative transition metal-based …

First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

A concise review on cobalt Schiff base complexes as anticancer agents

K Kar, D Ghosh, B Kabi, A Chandra - Polyhedron, 2022 - Elsevier
Research on metal-based chemotherapeutics gained tremendous impetus after the
groundbreaking discovery of cisplatin and related complexes as potential anticancer agents …

[HTML][HTML] Multifunctional metal–organic frameworks for wound healing and skin regeneration

F **ng, H Ma, P Yu, Y Zhou, R Luo, Z **ang… - Materials & Design, 2023 - Elsevier
Various wounds caused by burns, trauma, surgery, and genetic irregularities, including
acute and chronic wounds, pose a huge burden on global healthcare. Many therapeutic …

A review of the health hazards posed by cobalt

DJ Paustenbach, BE Tvermoes, KM Unice… - Critical reviews in …, 2013 - Taylor & Francis
Cobalt (Co) is an essential element with ubiquitous dietary exposure and possible
incremental exposure due to dietary supplements, occupation and medical devices. Adverse …

Advances of metallodrug-amyloid β aggregation inhibitors for therapeutic intervention in neurodegenerative diseases: Evaluation of their mechanistic insights and …

HY Khan, A Ahmad, MN Hassan, YH Khan… - Coordination Chemistry …, 2024 - Elsevier
Metal ions play a key role in aggregation of amyloid β protein by interfering with their proper
folding, altering protein homeostasis and cell viability, and ultimately leading to …