Extracellular Vesicles: Potential Role in Remote Signaling and Inflammation in Trypanosoma cruzi-Triggered Disease
L Dantas-Pereira, R Menna-Barreto… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) act as cell communicators and immune response modulators
and may be employed as disease biomarkers and drug delivery systems. In infectious …
and may be employed as disease biomarkers and drug delivery systems. In infectious …
Co-exposure of cardiomyocytes to IFN-γ and TNF-α induces mitochondrial dysfunction and nitro-oxidative stress: implications for the pathogenesis of chronic chagas …
Infection by the protozoan Trypanosoma cruzi causes Chagas disease cardiomyopathy
(CCC) and can lead to arrhythmia, heart failure and death. Chagas disease affects 8 million …
(CCC) and can lead to arrhythmia, heart failure and death. Chagas disease affects 8 million …
SBC guideline on the diagnosis and treatment of patients with cardiomyopathy of chagas disease–2023
SciELO - Brazil - Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e Tratamento …
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e Tratamento …
[HTML][HTML] MiR-27a-3p suppresses cerebral ischemia-reperfusion injury by targeting FOXO1
W Li, Q Zhu, X Xu, X Hu - Aging (albany ny), 2021 - ncbi.nlm.nih.gov
Cerebral ischemia-reperfusion (CI/R) injury is a serious complication when treating patients
experiencing ischemic stroke. Although the microRNA miR-27a-3p reportedly participates in …
experiencing ischemic stroke. Although the microRNA miR-27a-3p reportedly participates in …
Unraveling the role of miRNAs as biomarkers in Chagas cardiomyopathy: Insights into molecular pathophysiology
HG Ribeiro, OA Galdino, KSC de Souza… - PLOS Neglected …, 2024 - journals.plos.org
Background Chagas cardiomyopathy (ChCM) is a severe form of Chagas disease and a
major cause of cardiovascular morbidity and mortality. The dysregulation of the immune …
major cause of cardiovascular morbidity and mortality. The dysregulation of the immune …
Circulating MicroRNAs and myocardial involvement severity in chronic Chagas cardiomyopathy
Background Chronic Chagas Cardiomyopathy (CCM) is characterized by a unique
pathophysiology in which inflammatory, microvascular and neuroendocrine processes …
pathophysiology in which inflammatory, microvascular and neuroendocrine processes …
Impairment of multiple mitochondrial energy metabolism pathways in the heart of Chagas disease cardiomyopathy patients
PC Teixeira, A Ducret, H Langen, E Nogoceke… - Frontiers in …, 2021 - frontiersin.org
Chagas disease cardiomyopathy (CCC) is an inflammatory dilated cardiomyopathy
occurring in 30% of the 6 million infected with the protozoan Trypanosoma cruzi in Latin …
occurring in 30% of the 6 million infected with the protozoan Trypanosoma cruzi in Latin …
LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR‐133b in myocardial fibrosis after myocardial infarction
S Zhang, N Wang, Q Ma, F Fan… - Cell Biology …, 2021 - Wiley Online Library
Myocardial fibrosis (MF) is one of the basic causes of many cardiovascular diseases.
Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA …
Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA …
Modulation of miR-145-5p and miR-146b-5p levels is linked to reduced parasite load in H9C2 Trypanosoma cruzi infected cardiomyoblasts
In the heart tissue of acutely Trypanosoma cruzi-infected mice miR-145-5p and miR-146b-
5p are, respectively, downregulated and upregulated. Here, we used the H9C2 rat …
5p are, respectively, downregulated and upregulated. Here, we used the H9C2 rat …
[HTML][HTML] Multi-therapeutic strategy targeting parasite and inflammation-related alterations to improve prognosis of chronic Chagas cardiomyopathy: a hypothesis …
J Lannes-Vieira - Memórias do Instituto Oswaldo Cruz, 2022 - SciELO Brasil
Chagas disease (CD), caused by infection by the protozoan parasite Trypanosoma cruzi,
presents as main clinical manifestation the chronic chagasic cardiomyopathy (CCC). CCC …
presents as main clinical manifestation the chronic chagasic cardiomyopathy (CCC). CCC …