Life with bacterial mechanosensitive channels, from discovery to physiology to pharmacological target
P Blount, I Iscla - Microbiology and Molecular Biology Reviews, 2020 - Am Soc Microbiol
General principles in biology have often been elucidated from the study of bacteria. This is
true for the bacterial mechanosensitive channel of large conductance, MscL, the channel …
true for the bacterial mechanosensitive channel of large conductance, MscL, the channel …
Diphtheria in Europe: current problems and new challenges
K Zakikhany, A Efstratiou - Future microbiology, 2012 - Taylor & Francis
Diphtheria, caused by toxigenic strains of Corynebacterium diphtheriae, is an ancient
disease with high incidence and mortality that has always been characterized by epidemic …
disease with high incidence and mortality that has always been characterized by epidemic …
Exoproteome and Secretome Derived Broad Spectrum Novel Drug and Vaccine Candidates in Vibrio cholerae Targeted by Piper betel Derived Compounds
Vibrio cholerae is the causal organism of the cholera epidemic, which is mostly prevalent in
develo** and underdeveloped countries. However, incidences of cholera in developed …
develo** and underdeveloped countries. However, incidences of cholera in developed …
Target-Pathogen: a structural bioinformatic approach to prioritize drug targets in pathogens
EJ Sosa, G Burguener, E Lanzarotti… - Nucleic acids …, 2018 - academic.oup.com
Available genomic data for pathogens has created new opportunities for drug discovery and
development to fight them, including new resistant and multiresistant strains. In particular …
development to fight them, including new resistant and multiresistant strains. In particular …
Genome-Based Drug Target Identification in Human Pathogen Streptococcus gallolyticus
Streptococcus gallolysticus (Sg) is an opportunistic Gram-positive, non-motile bacterium,
which causes infective endocarditis, an inflammation of the inner lining of the heart. As Sg …
which causes infective endocarditis, an inflammation of the inner lining of the heart. As Sg …
An In Silico Identification of Common Putative Vaccine Candidates against Treponema pallidum: A Reverse Vaccinology and Subtractive Genomics Based Approach
Sexually transmitted infections (STIs) are caused by a wide variety of bacteria, viruses, and
parasites that are transmitted from one person to another primarily by vaginal, anal, or oral …
parasites that are transmitted from one person to another primarily by vaginal, anal, or oral …
An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae
Corynebacterium diphtheriae (Cd) is a Gram-positive human pathogen responsible for
diphtheria infection and once regarded for high mortalities worldwide. The fatality gradually …
diphtheria infection and once regarded for high mortalities worldwide. The fatality gradually …
A new antibiotic with potent activity targets MscL
The growing problem of antibiotic-resistant bacteria is a major threat to human health.
Paradoxically, new antibiotic discovery is declining, with most of the recently approved …
Paradoxically, new antibiotic discovery is declining, with most of the recently approved …
A web resource for designing subunit vaccine against major pathogenic species of bacteria
Evolution has led to the expansion of survival strategies in pathogens including bacteria and
emergence of drug resistant strains proved to be a major global threat. Vaccination is a …
emergence of drug resistant strains proved to be a major global threat. Vaccination is a …
[PDF][PDF] In silico approach for mining of potential drug targets from hypothetical proteins of bacterial proteome
UNM Omeershffudin, S Kumar - Int J Mol Biol Open Access, 2019 - researchgate.net
An increase in expansion of antibiotic-resistant bacterial pathogens alarms the world's
population and creating a wave of the antibiotic apocalypse. The inclination of the death rate …
population and creating a wave of the antibiotic apocalypse. The inclination of the death rate …