Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
The mononuclear phagocyte system (MPS) has historically been categorized into
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …
responses according to peripheral cues. After four decades of research, we now know that …
GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c+ MHCII+ macrophages and dendritic cells
Dendritic cells (DCs) are key players in the immune system. Much of their biology has been
elucidated via culture systems in which hematopoietic precursors differentiate into DCs …
elucidated via culture systems in which hematopoietic precursors differentiate into DCs …
[HTML][HTML] Development and function of dendritic cell subsets
A Mildner, S Jung - Immunity, 2014 - cell.com
Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …
[HTML][HTML] Human inflammatory dendritic cells induce Th17 cell differentiation
E Segura, M Touzot, A Bohineust, A Cappuccio… - Immunity, 2013 - cell.com
Dendritic cells (DCs) are critical regulators of immune responses. Under noninflammatory
conditions, several human DC subsets have been identified. Little is known, however, about …
conditions, several human DC subsets have been identified. Little is known, however, about …
The role of dendritic cells in cancer and anti-tumor immunity
AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …
linking innate and adaptive immunity and maintaining tolerance. There is increasing …
Defining GM-CSF–and macrophage-CSF–dependent macrophage responses by in vitro models
DC Lacey, A Achuthan, AJ Fleetwood… - The Journal of …, 2012 - journals.aai.org
Abstract GM-CSF and M-CSF (CSF-1) induce different phenotypic changes in macrophage
lineage populations. The nature, extent, and generality of these differences were assessed …
lineage populations. The nature, extent, and generality of these differences were assessed …
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
B Everts, E Amiel, GJW Van Der Windt… - Blood, The Journal …, 2012 - ashpublications.org
TLR agonists initiate a rapid activation program in dendritic cells (DCs) that requires support
from metabolic and bioenergetic resources. We found previously that TLR signaling …
from metabolic and bioenergetic resources. We found previously that TLR signaling …
The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment
TP Brown, P Bhattacharjee, S Ramachandran… - Oncogene, 2020 - nature.com
GPR81 is a G-protein-coupled receptor for lactate, which is upregulated in breast cancer
and plays an autocrine role to promote tumor growth by tumor cell-derived lactate. Here we …
and plays an autocrine role to promote tumor growth by tumor cell-derived lactate. Here we …
Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity
J Svensson-Arvelund, S Cuadrado-Castano… - Nature …, 2022 - nature.com
Immunotherapies directly enhancing anti-tumor CD8+ T cell responses have yielded
measurable but limited success, highlighting the need for alternatives. Anti-tumor T cell …
measurable but limited success, highlighting the need for alternatives. Anti-tumor T cell …